Results 41 to 50 of about 6,872,310 (275)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Determinants of maize farmers willingness to pay for private extension services in Ejisu municipality, Ghana

Heliyon
In recent times, private sector involvement in extension services delivery in Ghana has increased. We assessed farmers' willingness to pay (WTP) for private extension services.
John-Eudes Andivi Bakang, Camillus Abawiera Wongnaa, Enoch Kwame Tham-Agyekum, Suraju Fatimatu, Jonathan Annorhene Obeng, Elsie Boatemah Nsafoah, Michael Asiedu Antwi   +6 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

ARE AGRICULTURAL EXTENSION SERVICES ACCESSIBLE TO GHANAIAN FARMERS? PROBABILITIES AND EXPECTATIONS FROM CORNER SOLUTION RESPONSES

Apstract: Applied Studies in Agribusiness and Commerce
Agricultural extension services play a vital role in Ghana’s vegetable sector modernization and growth agenda. The Government of Ghana has made efforts to enhance extension delivery by improving the Agricultural Extension Agent (AEA)-farmer ratio from 1:
Jacqueline Ninson, Daniel Ninson
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Improving Livestock Services Delivery by Mobile Veterinary Units in Odisha [PDF]

, 2017
Mobile Veterinary Unit (MVU), an ingenious way of livestock service delivery at the farmers’ doorstep is being operational under the Rastriya Krishi Vikas Yojana (RKVY) in all the 314 blocks of Odisha.
Mahesh Chander, Anupama Jena, Chander, Mahesh, Jena, Anupama   +3 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Role of the Three Tiers of Government in the Provision of Sustainable Agricultural Extension Service in Nigeria

Journal of Agricultural Extension, 2014
This paper focused on how the three tiers of government actually work in delivering extension services, and whether there is synergy of responsibilities—both financial and managerial—to improve accountability and performance.
F O Issa, A B Aminu, A Y Abdullahi, M A Abdulazeez   +3 more
doaj   +4 more sources

Community perception of barriers and facilitators to institutional delivery care-seeking behavior in Northwest Ethiopia: a qualitative study

Reproductive Health, 2022
Plain language summary Institutional delivery plays a critical role in the prevention of maternal death and improves newborn health. Although most of maternal health services were free of charge in Ethiopia, institutional delivery is low in the rural ...
Adane Nigusie, Telake Azale, Mezgebu Yitayal, Lemma Derseh   +3 more
doaj   +1 more source