Results 61 to 70 of about 6,723,237 (315)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Firstly, based on the river health evaluation theory and starting from the integrity of the river system, the river health evaluation index system is selected.
Ke Zhou
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A Possible Extension of Shannon's Information Theory
: As a possible generalization of Shannon's information theory, we review the formalism based on the non-logarithmic information content parametrized by a real number q, which exhibits nonadditivity of the associated uncertainty.
Takuya Yamano
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The increasing demand for power quality in modern power supply facilities and the deepening changes in the power market have led to frequent power quality events, making the assessment of power quality a necessity.
Jingyi Zhang +6 more
doaj +1 more source
Holography of massive M2-brane theory: non-linear extension
We investigate the gauge/gravity duality between the $$\mathcal{N} = 6$$ N=6 mass-deformed ABJM theory with $$\hbox {U}_k(N)\times \hbox {U}_{-k}(N)$$ Uk(N)×U-k(N) gauge symmetry and the 11-dimensional supergravity on LLM geometries with SO(2,1)$$\times $
O-Kab Kwon +3 more
doaj +1 more source
CURRENT-VOLTAGE CHARACTERISTICS FOR TWO SYSTEMS OF QUANTUM WAVEGUIDES WITH CONNECTED QUANTUM RESONATORS [PDF]
We investigate two 2D quantum systems, each consisting of a waveguide and a resonator, connected through narrow holes. Systems features are studied by the solution of scattering problem.
A. S. Bagmutov, I. Y. Popov
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

