Results 281 to 290 of about 1,611,794 (333)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Combined and interaction effects of outdoor and reading time on myopia onset: evidence from over 210 000 schoolchildren in China. [PDF]

J Glob Health
Li J, Liu S, Zhu Y, Song D, Jin N, Tang C, Li X, Zhang B, Su J, Wei R, Du B.   +10 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

All together now: Random Forests analysis reveals the joint impact of multiple statistical regularities on eye-movements during reading. [PDF]

Psychon Bull Rev
Kimchi I, Siegelman N.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Validation of the EYEMATE-SC Suprachoroidal Pressure Transducer for Telemetric Measurement of Intraocular Pressure in Normal Ex Vivo Canine and Equine Globes-Preliminary Results. [PDF]

Vet Ophthalmol
Buckman PN, Brinker BA, Kapeller LE, Komáromy AM.   +3 more
europepmc   +1 more source

Replicate Me if You Can: Assessing Measurement Reliability of Individual Differences in Reading Across Measurement Occasions and Methods. [PDF]

Cogn Sci
Haller P, Ding C, Stegenwallner-Schütz M, Reich DR, Koncic I, Makowski S, Jäger LA.   +6 more
europepmc   +1 more source

Beyond the ‘Uh-Oh’ Moment: Refusal Strategies in a Young EFL Learner’s Extensive Reading Responses

Zalva Fajhira Shabrina Putri, Utami Widiati, Evynurul Laily Zen   +2 more
openalex   +1 more source

Impact of Simulated Astigmatism on Visual Acuity, Stereopsis, and Reading in Young Adults. [PDF]

Vision (Basel)
Shato CWM, Louzada RN, Magalhães PLM, Amaral DC, Dantas DO, Montenegro DA, Chow MM, Tayah D, Alves MR.   +8 more
europepmc   +1 more source