Results 91 to 100 of about 164,028 (280)
Journal of Ultrasonography, 2020 Aim of the study: To assess the features identified on ultrasound in patients presenting with suspected extensor pollicis longus tendon rupture, and correlate this with surgical findings.
Ghazal Louy +3 more
doaj +1 more source
Physical Activity Modulates Corticospinal Excitability of the Lower Limb in Young and Old Adults [PDF]
, 2017 Aging is associated with reduced neuromuscular function, which may be due in part to altered corticospinal excitability. Regular physical activity (PA) may ameliorate these age-related declines, but the influence of PA on corticospinal excitability is ...
Hassanlouei, Hamidollah +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Indian Journal of Plastic SurgeryDelayed rupture of extensor tendons of hand can occur due to a variety of reasons. Post-traumatic attrition rupture of extensor pollicis longus (EPL) tendon following distal radius fractures is well known.
Maksud Mubarak Devale +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sublinear Higson corona and Lipschitz extensions [PDF]
, 2006 The purpose of the paper is to characterize the dimension of sublinear Higson corona $\nu_L(X)$ of $X$ in terms of Lipschitz extensions of functions: Theorem: Suppose $(X,d)$ is a proper metric space. The dimension of the sublinear Higson corona $\nu_L(
Cencelj, M. +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Initial neuromuscular performance in older women influences response to explosive resistance training [PDF]
, 2009 The purpose of the study was to identify both demographic and neuromuscular traits that characterize successful or unsuccessful adaptation to resistance training in older women.
LaRoche, Dain P.
core +1 more source