Results 41 to 50 of about 2,405,589 (265)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Perilaku Wirausaha Industri Keramik Berskala Kecil untuk Meningkatkan Daya Saing Produk di Malang

open access: yesJurnal Manajemen dan Wirausaha, 2008
The purposes of the study was to find out the explanation of ceramic entrepreneurs’ respond to the environment factors affecting competitiveness of small scale ceramic industries (SSCIs).
Sri Hadiati
doaj  

Examination of the Relationships between Internal and External Egg Quality Traits: A Structural Equation Model

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2023
This study aimed to determine the structural relationship between internal and external egg quality (IEEQ) traits. In this study, 114 eggs produced from 24 weeks-old laying hens reared at the Ondokuz Mayis University Research Farm were used.
Samet Hasan Abacı   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The results of arthroscopically assisted circular external fixation in bicondylar tibial plateau fractures

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objectives: We evaluated the results of arthroscopically assisted circular external fixation in bicondylar tibial plateau fractures. \nMethods: The study included 13 patients (12 males, 1 female; mean age 27 years; range 18 to 37 years) who were treated ...
Erbil Oguz   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Simplified Technique for Orientation of a Bone Anchored Auricular Prostheses: a Clinical Report

open access: yeseJournal of Oral Maxillofacial Research, 2012
Background: A simple technique was presented in this clinical report for orientation of a bone anchored auricular prosthesis.Methods: The proposed technique includes drawing the intact ear on a transparent celluloid paper or radiographic film and ...
Hussein G. El Charkawi   +1 more
doaj  

External ophthalmomyiasis caused by oestrus ovis larvae

open access: yesIndian Journal of Ophthalmology. Case Reports
A 17 year-old man presented with redness, foreign body sensation, and itching in his right eye for a day after some dust particles fell into his eyes.
Shantanu K Sharma   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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