Results 121 to 130 of about 65,480 (254)

Long‐Term Clinical Response After Low‐Dose and Short‐Duration Cemiplimab Therapy in a Patient With Xeroderma Pigmentosum in Nepal

open access: yesJEADV Clinical Practice, EarlyView.
Capsule Summary Xeroderma pigmentosum (XP) is associated with a high risk of multiple and aggressive cutaneous squamous cell carcinomas (CSCCs). The immune checkpoint inhibitor cemiplimab has been approved in advanced, unresectable, and/or metastatic CSCCs.
Sudip Parajuli   +5 more
wiley   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang   +5 more
wiley   +1 more source

Structural Carotid Atherosclerosis and Mild Behavioral Impairment: A Cross‐Sectional Study in a Community‐Dwelling Population

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mild behavioral impairment (MBI) is a late‐life neuropsychiatric syndrome proposed as an early clinical manifestation of neurodegenerative disease. Vascular pathology contributes to late‐life cognitive and behavioral changes; however, its relationship with MBI remains insufficiently characterized.
Po‐Han Chen   +6 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra   +3 more
wiley   +1 more source

Office‐Based Transoral Ultrasonography in the Diagnostic Workup of Oropharyngeal Cancer

open access: yesThe Laryngoscope, EarlyView.
This article demonstrates how to perform and interpret transoral ultrasound of the palatine and lingual tonsils in patients with suspected oropharyngeal cancer. This technique offers a reliable adjunct to conventional assessment but requires substantial operator experience and patient cooperation.
Amalie P. Posselt   +2 more
wiley   +1 more source

Pseudoaneurysm of the external carotid artery following parotitis: a case report. [PDF]

open access: yesAnn Med Surg (Lond), 2023
Nahal C   +4 more
europepmc   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

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