Results 121 to 130 of about 693,569 (261)

Racial and Ethnic Disparities in Estimated Excess Mortality From External Causes in the US, March to December 2020.

open access: yesJAMA Intern Med, 2022
Chen R   +6 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Assessment of incompleteness of Mortality Information System records on deaths from external causes in the state of Rio Grande do Sul, Brazil, 2000-2019. [PDF]

open access: yesEpidemiol Serv Saude, 2023
Barbosa JS   +7 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Análise Comparativa dos Óbitos de Médicos e Advogados Periciados no IML-BH no Período de 2006 a 2012

open access: yesBrazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2017
As causas externas apresentam distribuição desigual entre diferentes grupos populacionais. Esta pesquisa buscou verificar se há diferença nos óbitos por causas externas entre médicos e advogados, profissões de um mesmo grupo socioeconômico. Foi realizado
Polyanna Helena Coelho Bordoni   +5 more
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Trends in mortality from external causes in the Republic of Seychelles between 1989 and 2018. [PDF]

open access: yesSci Rep, 2020
Abio A   +6 more
europepmc   +1 more source

Evaluation of the mortality due to external causes.

open access: yesRevista do Colegio Brasileiro de Cirurgioes, 2013
External causes have become an important public health problem due to their high mortality, morbidity, costs, the loss of potential years of life and the impact for individuals, their families and society. The aim of this study was to analyze the characteristics of fatal victims of trauma in a microregion from São Paulo State.This was a retrospective ...
Ricardo Alessandro Teixeira, Gonsaga   +5 more
openaire   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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