Results 111 to 120 of about 936,741 (303)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Development of a dosimeter for distributed body organs [PDF]

Calculational methods for estimation of dose from external proton exposure of aribtrary convex bodies is briefly reviewed and all of the necessary information for the estimation of dose in soft tissue is presented.
Khandelwal, G. S.
core   +1 more source

SpaceOAR to improve dosimetric outcomes for monotherapy high-dose-rate prostate implantation in a patient with ulcerative colitis. [PDF]

, 2018
High-dose-rate (HDR) brachytherapy is an attractive option for patients receiving definitive radiation therapy for prostate cancer with decreased overall dose to the pelvis.
Den, Robert B., Greenberger, Benjamin, Harrison, Amy S., Keller, James, Trager, Michael   +4 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The 90% effective dose of spinal ropivacaine for external cephalic version: A sequential dose-finding study

Journal of International Medical Research
Objective Although spinal anesthesia can improve the success of external cephalic version, the optimal analgesic dose of ropivacaine remains undefined, and higher doses may increase potential risks. This study aimed to determine the 90% effective dose of
Qiao Shi, Jing Zheng, Tao Xu, Jing Chai, Rui Ma   +4 more
doaj   +1 more source

Impact of radiation dose on nuclear shuttle configuration [PDF]

, 1972
The impact of nuclear radiation (from the NERVA propulsion system) on the selection of a reference configuration for each of two classes of the reusable nuclear shuttle is considered.
Billings, M. A., Goetz, C. A.
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Modification of intergrain connectivity, upper critical field anisotropy, and critical current density in ion irradiated MgB2 films

, 2005
We study the effect of 100 MeV Silicon and 200 MeV Gold ion irradiation on the inter and intra grain properties of superconducting thin films of Magnesium Diboride.
Bean, Bouquet, Braccini, Bu, C.B. Eom, Canfield, Chikumoto, Choi, D.M. Kim, Dou, Ferrando, Gandikota, Gerhäuser, Giubileo, Gurevich, Gurevich, Iavarone, J.E. Giencke, Liu, Mazin, Okayasu, P.K. Mishra, Patnaik, Putti, Putti, Ravi Kumar, Rowell, S. Patnaik, S.D. Kaushik, Shinde, Szabo, Ziegler   +31 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source