Results 241 to 250 of about 525,073 (300)

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik   +6 more
wiley   +1 more source

Intensive Swallowing Rehabilitation for Head and Neck Cancer Survivors With Chronic Dysphagia: Outcomes From a Prospective Multicentre Cohort Study With 6‐Month Follow‐Up

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Chronic dysphagia persists in some head and neck cancer (HNC) survivors despite preventive exercises, negatively impacting quality of life. Evidence for effective rehabilitation strategies remains limited. Methods This prospective cohort study included 34 HNC survivors (≥ 1 year post‐treatment) who completed a 3‐week intensive ...
J. I. Oldenbeuving   +3 more
wiley   +1 more source

Anatomical Variation of Absent Facial Vein: Implications for Facial Reanimation Surgery

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The facial vein is the standard recipient vessel in facial reanimation surgery. Its complete absence is rarely described but may cause major challenges during free functional muscle transfer (FFMT). This study aimed to determine the prevalence and predictors of facial vein absence and assess its surgical relevance in facial ...
Cam T. Nguyen   +4 more
wiley   +1 more source

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder   +11 more
wiley   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su   +8 more
wiley   +1 more source

Deep Learning for Pretreatment Imaging‐Based Tumor and Nodal Classification in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Network Meta‐Analysis

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Accurate pretreatment assessment of the extent of tumor invasion and status of cervical lymph node metastasis is essential for staging and treatment planning in HNSCC. Deep learning (DL) shows promise but is limited by methodological heterogeneity. Methods We conducted a systematic review and network meta‐analysis (PRISMA). Studies (
Jannik Ketschau   +10 more
wiley   +1 more source

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