Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Clinical and Radiological Outcomes of Schatzker Type V and VI Tibial Plateau Fractures Treated With Internal Fixation and External Fixation. [PDF]
Ali U +6 more
europepmc +1 more source
The first cryo‐EM visualization and quantification of oriented Photosystem I (PSI) on single‐layer graphene is reported. Domain‐specific covalent anchoring of PSI, with the reducing side of the biophotocatalyst toward graphene, promotes three‐fold higher anodic photocurrent generation compared to a randomly physisorbed counterpart. This approach allows
Miriam Izzo +6 more
wiley +1 more source
Reassessing the role of external fixation in polytrauma and severly injured patients with chest trauma and femur fracture: a propensity score-matched analysis from the TraumaRegister DGU<sup>®</sup>. [PDF]
Keß A +3 more
europepmc +1 more source
Steep‐Switching Memory FET for Noise‐Resistant Reservoir Computing System
We demonstrate the steep‐switching memory FET with CuInP2S6/h‐BN/α‐In2Se3 heterostructure for application in noise‐resistant reservoir computing systems. The proposed device achieves steep switching characteristics (SSPGM = 19 mV/dec and SSERS = 23 mV/dec) through stabilization between CuInP2S6 and h‐BN.
Seongkweon Kang +6 more
wiley +1 more source
Imaging and clinical efficacy analysis of minimally invasive reduction and crossbar external fixation in the treatment of Sanders Ⅱ and Ⅲ calcaneal fractures. [PDF]
Wang J, Guan T, Xue Q.
europepmc +1 more source
Electroactive Metal–Organic Frameworks for Electrocatalysis
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska +7 more
wiley +1 more source
[Basic knowledge and skills required in external fixation and foot and ankle reconstruction]. [PDF]
Qin S, Du H.
europepmc +1 more source
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato +9 more
wiley +1 more source
MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani +9 more
wiley +1 more source

