Results 31 to 40 of about 175,412 (261)
BMC Musculoskeletal DisordersBackground Acetabular fractures typically require open surgery to restore hip joint function. Openness may lead to serious tissue damage, increased bleeding, and the risk of nerve and vascular damage.
Zhen Xia +7 more
doaj +1 more source
Acta Orthopaedica et Traumatologica Turcica, 2020 Objectives: This study was designed to compare the results of palmar locking plate and K-wire augmented external fixation in the treatment of intra-articular comminuted distal radius fractures.
Arel Gereli +3 more
doaj +1 more source
Cerrahpaşa Medical Journal, 2022 Objective: This study aims to evaluate the patients with Charcot neuropathy and look for differences in fusion rate, limb salvage rate, and complications following external fixation and internal fixation used in tibiotalar/tibiocalcaneal arthrodesis ...
Necip Selcuk Yontar, Tahir Öğüt
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of Experimental OrthopaedicsPurpose While rigid knee‐spanning external fixation is more commonly utilized in the treatment of complex knee injuries compared to hinged external fixation (HEF), HEF has the added benefit of providing stability while also permitting early controlled ...
Ekrem M. Ayhan +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A systematic review of incidence of pin track infections associated with external fixation
Journal of Limb Lengthening & Reconstruction, 2016 Depending on the reference, pin track infection rates in external fixation surgery have been stated to be anywhere from 0% to 100%. We critically evaluated the pin track infection rate for external fixation by performing systematic review of the external
Christopher A Iobst, Raymond W Liu
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source