Results 61 to 70 of about 93,846 (259)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The Relations of Locus of Control and Behavioral Approach and Inhibition Systems to General Health in Elderly Nursing Home Residents in Dubai

open access: yesSālmand, 2020
Objectives: This article aimed to study the relations of locus of control and behavioral approach/inhibition systems to general health in elderly nursing home residents in Dubai.
Majid Saffarinia, Atousa Mehdizadeh
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Coping with stress in the workplace

open access: yesSA Journal of Industrial Psychology, 2008
The researchers investigated a simplified process model, a so-called salutogenic approach, of coping with stress in the workplace. Two constructs of salutogenic functioning, namely sense of coherence and locus of control (three dimensions: internal ...
Janine D. Oosthuizen, Burger van Lill
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Prediction of Procrastination Considering Job Characteristics and Locus of Control in Nurses

open access: yesJournal of Holistic Nursing and Midwifery, 2017
Introduction: Procrastination is a behavioral habit, described as putting off the tasks. The behavioral habit in nursing profession because of its nature is natural and tangible.
Mahdieh Sadat Khoshouei
doaj  

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