Results 111 to 120 of about 2,254,256 (310)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Making it real: information literacy and student engagement [PDF]

open access: yes, 2008
In recent years Irish universities have expanded and diversified in response to a changing external environment. A key factor in this change is the increasing acceptance of the importance of lifelong learning. This drive to produce quality graduates, who
Byrne, Ursula, Dunne, Siobhán
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Performance of Portuguese laboratories in Labquality/PNAEQ EQA schemes for N. gonorrhoeae and C. trachomatis nucleic acid detection [PDF]

open access: yes, 2013
The National External Quality Assessment Program (PNAEQ) includes the National Health Institute Dr. Ricardo Jorge (INSA, IP), which is legally responsible for the promotion, organization and coordination of External Quality Assessment Laboratory programs.
Brito, Cristina   +4 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

The Danish external quality assessment scheme.

open access: yesAnnali dell'Istituto superiore di sanita, 1996
Participation in proficiency testing schemes is generally recognized as an important part of quality control in analytical chemistry. The design and conduct of proficiency testing schemes is therefore a matter of great importance. A proficiency testing scheme should: a) cover a broad concentration range of the substance of interest; b) enable the ...
J M, Christensen, J, Kristiansen
openaire   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Capturing impacts of Leader and of measures to improve Quality of Life in rural areas [PDF]

open access: yes
The Helpdesk of European Evaluation Network for Rural Development supported by a group of external experts has prepared a Working Paper on ”Capturing the impacts of Leader and measures to improve the Quality of life (QoL) in rural areas”.
Brakalova, Marina   +14 more
core   +1 more source

Измерения в образовании и углубленное изучение литературы [PDF]

open access: yes, 2014
Перспективним шляхом підвищення якості освіти є ефективне використання новітніх освітніх вимірювань, зокрема – зовнішнього незалежного оцінюванням (ЗНО) результатів навчання.
Ковбасенко, Юрій Іванович
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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