Results 161 to 170 of about 3,008,012 (393)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Quality of Same-Day Sputum Smears Microscopy and Presumptive Tuberculosis Patients Drop-out at Health Facilities of Addis Ababa, Ethiopia

Tuberculosis and Respiratory Diseases, 2020
Background Same-day sputum microcopy is recommended in areas where sputum smear microscopy external quality assessment (EQA) is effectively implemented and sturdy.
Boja Dufera Taddese, M.Sc., Abay Sisay Misganaw, M.Sc   +1 more
doaj  

Patient self‐management of oral anticoagulation and external quality assessment procedures [PDF]

, 2003
Ellen Murray, Dianne Kitchen, Steve Kitchen, Ian Jennings, Tim Woods, F E Preston, David Fitzmaurice   +6 more
openalex   +1 more source

Performance of Portuguese laboratories in Labquality/PNAEQ EQA schemes for N. gonorrhoeae and C. trachomatis nucleic acid detection [PDF]

, 2013
The National External Quality Assessment Program (PNAEQ) includes the National Health Institute Dr. Ricardo Jorge (INSA, IP), which is legally responsible for the promotion, organization and coordination of External Quality Assessment Laboratory programs.
Brito, Cristina, Correia, Helena, Faria, Ana Paula, Pelanti, Jonna, Silva, Rita   +4 more
core  

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

Changing assessment practice in engineering: how can understanding lecturer perspectives help?

, 2004
Assessment in engineering disciplines is typically oriented to demonstrating competence in specific tasks. Even where assessments are intended to have a formative component, little priority may be given to feedback.
Baillie C, Becher T, Biggs J, Black P, Case J, Gipps CV, Hugh C. Davis, Liz McDowell, Prosser M, Su White   +9 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Twelve years of the Brazilian External Quality Assessment Program in Immunohematology: benefits of the program [PDF]

, 2005
Laércio Deleon de Melo, J. Pellegrino, Celso Bianco, Lilian Castilho   +3 more
openalex   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Quality control in the histopathology laboratory: An overview with stress on the need for a structured national external quality assessment scheme

Indian Journal of Pathology and Microbiology, 2009
The concept of quality control in histopathology is relatively young and less well understood. Like in other disciplines of laboratory medicine, the concept of quality and its control is applicable to pre analytical, analytical and post analytical ...
Iyengar Jayaram
doaj