Results 191 to 200 of about 3,008,012 (393)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

External quality assessment in histopathology: an overview. [PDF]

Journal of Clinical Pathology, 1989
openaire   +3 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

An Internet-based external quality assessment in cytogenetics that audits a laboratory's analytical and interpretative performance [PDF]

, 2008
Rosalind J. Hastings, Eddy Maher, Bettina Quellhorst-Pawley, Rodney T Howell   +3 more
openalex   +1 more source

The Workplace Simulation Project [PDF]

, 2015
Undergraduate students often seek voluntary placements in diagnostic laboratories in order to gain work experience to enhance their employment prospects.
Ferrier, C., Ferrier, C.
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

International external quality assessment scheme for the laboratory diagnosis of diphtheria

, 2001
Kathryn H. Engler, Roman S. Kozlov, STEVEN J. COPPING, MEMBERS OF THE EUROPEAN LABORATORY WORKING GROUP ON DIPHTHERIA, Androulla Efstratiou   +4 more
openalex   +1 more source

Large-scale affordable Panleucogated CD4⁺testing with proactive internal and external quality assessment: In support of the South African national comprehensive care, treatment and management programme for HIV and AIDS [PDF]

, 2008
Deborah K. Glencross, George Janossy, Lindi M. Coetzee, Denise Lawrie, Hazel Aggett, Lesley Scott, Ian Sanne, James McIntyre, Wendy Stevens   +8 more
openalex   +1 more source

Card games are effective tools to enhance foundation year health and safety inductions

FEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq, Holly Matthews, Daniya Abedalreza, Faten Yahya, Matthew Allan Jones   +4 more
wiley   +1 more source

African regional external quality assessment for CD4 T-cell enumeration: Development, outcomes, and performance of laboratories [PDF]

, 2008
Deborah K. Glencross, Hazel Aggett, Wendy Stevens, Frank Mandy   +3 more
openalex   +1 more source