Results 21 to 30 of about 2,254,256 (310)

Challenges in next generation sequencing of homology recombination repair genomic variants in prostate cancer: A nationwide survey and calibration project in China

Prostate International, 2022
Background: Homologous Recombination Repair (HRR) is the most reliable and important signaling pathway for repairing DNA damage. We initiated a calibration project to better understand the NGS landscape for HRR gene testing in China, provide indications ...
Huanwen Wu, Liqun Zhou, Xiaoyan Zhou, Qiang Wei, Nengtai Ouyang, Jianyong Shao, Jian Huang, Zhiyong Liang   +7 more
doaj   +1 more source

Managing Deviating EQA Results: A Survey to Assess the Corrective and Preventive Actions of Medical Laboratories Testing for Oncological Biomarkers

Diagnostics, 2020
Laboratories testing predictive biomarkers in lung and colorectal cancer are advised to participate in external quality assessment (EQA) schemes. This study aimed to investigate which corrective actions were taken by laboratories if predetermined ...
Cleo Keppens, Ed Schuuring, Elisabeth MC Dequeker   +2 more
doaj   +1 more source

External quality assessment of molecular biology-based methods used in laboratories of clinical chemistry and human genetics [PDF]

, 1998
The Reference Institute of Bioanalysis of the German Society of Clinical Chemistry has performed the first external assessment of molecular genetics methods used in medical diagnosis.
Braun, Andreas, Deufel, Thomas, Geilenkeuser, Wolf-Jochen, Neumaier, Michael, Roscher, Adelbert, Röhle, Gerhard, Wagener, Christoph   +6 more
core   +1 more source

External quality assessment of hormone determinations

Best Practice & Research Clinical Endocrinology & Metabolism, 2013
Hormone determinations are of central importance to the practice of Clinical Endocrinology, and ensuring their correct use and performance is a multidisciplinary responsibility involving clinicians, laboratory staff, manufacturers of diagnostic systems and healthcare regulatory agencies.
openaire   +2 more sources

Inter‐rater agreement of HER2‐low scores between expert breast pathologists and the Visiopharm digital image analysis application (HER2 APP, CE2797)

The Journal of Pathology: Clinical Research
Inter‐observer concordance data for the HER2 category as assessed by a group of 16 specialist breast pathologists on 50 diagnostic core biopsies was compared with that produced by digital image analysis (DIA) using the HER2 APP, CE2797 (VP APP ...
Suzanne Parry, Lila Zabaglo, Abeer M Shaaban, Andrew Dodson   +3 more
doaj   +1 more source

Networking of Public Health Microbiology Laboratories Bolsters Europe’s Defenses against Infectious Diseases

Frontiers in Public Health, 2018
In an era of global health threats caused by epidemics of infectious diseases and rising multidrug resistance, microbiology laboratories provide essential scientific evidence for risk assessment, prevention, and control. Microbiology has been at the core
Barbara Albiger, Joana Revez, Katrin Claire Leitmeyer, Marc J. Struelens   +3 more
doaj   +1 more source

External Quality Assessment for Next-Generation Sequencing-Based HIV Drug Resistance Testing: Unique Requirements and Challenges

Viruses, 2020
Over the past decade, there has been an increase in the adoption of next generation sequencing (NGS) technologies for HIV drug resistance (HIVDR) testing.
Emma R. Lee, Feng Gao, Paul Sandstrom, Hezhao Ji   +3 more
doaj   +1 more source

Towards Research Excellence for Development: The Research Quality plus (RQ+) Assessment Instrument [PDF]

, 2014
This document presents a framework and practical guidelines for assessing the quality of research for development. Referred to as the "RQ+"1 assessment instrument, it serves as a tool to guide the work of external evaluators hired by IDRC as part of the ...

core  

External quality assessment of urinary steroid profile analysis [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2004
Background: Clinical samples were distributed on 10 occasions to six UK laboratories that perform urinary steroid profile analysis. Urine samples were from normal adult men and women, normal children and neonates. Samples from patients with Cushing's syndrome, virilization, adrenarche, obesity and congenital adrenal hyperplasia (21 and 17-hydroxylase ...
I J, Phillips, E M, Conway, R A, Hodkinson, J W, Honour   +3 more
openaire   +2 more sources

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source