Results 131 to 140 of about 75,087 (309)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Where Do Human Capital Externalities End Up To? [PDF]
Recent literature has aimed at evaluating human capital externalities by estimating the effect of human capital on wages at urban level. We argue that this methodology might not identify properly human capital spillovers.
Alberto Dalmazzo, Guido De Blasio
core
Dead weight loss associated with economic efficiency use of esticides in Indonesian rice production
Economic Journal of Emerging Markets, 2014 This paper analyses the efficient use of pesticides by internalizing the costs of externality, and estimates the monetary value of welfare loss. The benefit of pesticide use is estimated using a production function, and the economic value of the adverse
Joko Mariyono
doaj
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Valuing Externalities: A methodology for urban water use [PDF]
This report provides a methodology and framework for valuing externalities associated with urban water use.Australia;urban water ...
Mike Young
core
Sobre el desarrollo de la teoría de los bienes públicos locales
Revista Finanzas y Política Económica, 2009 La teoría de los bienes públicos locales toma forma desde la concepciónde la hipótesis de Tiebout, que es el primer planteamiento que tuvo en cuentala dimensión espacial de los bienes públicos, y constituye un mecanismo para la revelación de las ...
Miltón Samuel Camelo
doaj
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Human Capital Externalities in Western Germany [PDF]
The paper sheds light on the impact of spatial agglomeration of human capital on individual wages in Western Germany. Using panel data it shows that regional wage differentials are to a large extent attributable to localized human capital externalities ...
Daniel F. Heuermann
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Identification of Network Externalities in Markets for Non-Durables [PDF]
This paper introduces a structural econometric model of consumer demand for non-durable goods, which exhibits network externalities. The structural model allows us to identify the parameters, which determine the strength of the externalities in the ...
Michal Grajek
core