Results 161 to 170 of about 112,775 (298)
Species conservation in the face of political uncertainty [PDF]
Recent political developments and academic debate indicate that future political commitment to the protection of natural resources is uncertain. This political uncertainty is particularly problematic when the danger of irreversible damage such as the ...
Wätzold, Frank, Drechsler, Martin
core
Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics
Angewandte Chemie, EarlyView.This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang +9 more
wiley +2 more sources
Why "Extinction" Is a Human Label, Not a Biological Event
How CMEM, NIRM, RNB, ITT, and IFST diagnose systems (one coherent toolchain) This work treats any physical, biological, cognitive, or civilizational process as an interface-assembly: signals enter, circulate, and exit under constraints. The framework is diagnostic (descriptive), not prescriptive—it does not encode purpose, optimization, morality ...
openaire +1 more source
Angewandte Chemie, EarlyView.Red‐emissive carbon dots (R‐CDs) exhibiting aggregation‐induced emission (AIE) and aggregation‐caused quenching (ACQ) effects are synthesized from citric acid and urea. They display weak blue fluorescence in water but strong red emission in DMF due to aggregation.
Jiafeng Wan +11 more
wiley +2 more sources
Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy
Angewandte Chemie, EarlyView.We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu +10 more
wiley +2 more sources
Sexually dimorphic effects of single prolonged stress on conditioned suppression behavior in Long Evans rats with no detection of altered mRNA expression of VGLUT1, GAD1, and Arc in the ventral hippocampus. [PDF]
Front Behav NeurosciPitcairn SR +3 more
europepmc +1 more source
Extinction risk assessment as a tool for biological conservation
, 2013 Effective conservation of biological diversity requires accurate assessments of species extinction risks. Both under- and over-estimating extinction risks can have serious consequences.
Stanton, Jessica Carol
core
Angewandte Chemie, EarlyView.A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang +12 more
wiley +2 more sources
Rethinking viral evolution: How BIAS mechanisms and Gamma-Poisson overdispersion redefine lethal mutagenesis. [PDF]
Front MicrobiolWang D, Zhang X, Chang Q.
europepmc +1 more source
2‐Azaazulenium Hemicyanine Dyes for NIR‐II Multimodal Imaging and Combined Phototherapy
Angewandte Chemie, EarlyView.A strategically engineered class of 2‐azaazulenium hemicyanines is developed, featuring bright fluorescence in the second near‐infrared (NIR‐II) window and multifunctional performance. SWJT‐OCH3 shows type I/II reactive oxygen species (ROS) generation and excellent photothermal activity.
Min Peng +8 more
wiley +2 more sources