Results 241 to 250 of about 948,700 (330)

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

A mechanistic trial of the neurobiology of extinction learning and intraparietal sulcus stimulation: Protocol. [PDF]

Contemp Clin Trials Commun
Joshi SA, Lin T, Balderston NL, Lynch KG, Tang M, Patel M, Sun I, Fureman B, Oathes DJ, Gregory DF, Sheline YI, Brown LA.   +11 more
europepmc   +1 more source

Mechanisms of hunting native megafauna to extinction by Palaeolithic humans on Cyprus [PDF]

Corey J. A. Bradshaw, Frédérik Saltré, Stefani A. Crabtree, Christian Reepmeyer, Theodora Moutsiou   +4 more
openalex   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

Neural and physiological correlates of parent-child observational threat extinction. [PDF]

Sci Rep
Heyn SA, Herringa RJ.
europepmc   +1 more source

The significance of impact-induced hydrocarbon soot aerosols in global climate change and extinctions

Kunio Kaiho, Naga Oshima
openalex   +1 more source

Visualizing Strain‐Coupled Cryogenic Phase Transitions and Defect Dynamics in Perovskite Quantum Dots Using In Situ STEM

Advanced Science, EarlyView.
Cryogenic cooling induces an orthorhombic‐to‐monoclinic phase transition in CsPbBr3 quantum dots, accompanied by pronounced strain localization at surfaces and interfaces. Multimodal in situ STEM directly visualize reversible defect healing during moderate cryogenic treatment and irreversible degradation upon prolonged exposure, revealing the intrinsic
Xinjuan Li, Zhao Jiang, Si Chen, Yi Tang, Bofeng Xue, Tianhao Wu, Yang Lu, Xavier Moya, Akshay Rao, Zhongzheng Yu, Caterina Ducati   +10 more
wiley   +1 more source

Vagus nerve stimulation modulates cocaine seeking induced synaptic plasticity in reward related brain circuits. [PDF]

Sci Rep
Arezoomandan R, Vu L, Driskill C, Kroener S.   +3 more
europepmc   +1 more source

The Extinction of Traditional Shopping as a Consequence of the Technological and Generational Transition - an Empirical Study Applied in Portugal

Felipa Lopes dos Reis, João de Freitas Martins Gonçalves Pestana   +1 more
openalex   +1 more source

Arbitrary 3D Organic Mixed Ionic‐Electronic Conductor Architectures via Self‐Fusion of PEDOT:PSS Microfibers

Advanced Science, EarlyView.
A general fabricating strategy for arbitrary 3D organic mixed ionic‐electronic conductor architectures is reported using PEDOT:PSS microfiber building blocks. A water‐assisted self‐fusion process is successfully developed in which adhesion can be modulated as reversible (PSS‐rich) or irreversible (PEDOT‐rich) self‐fusion depending on the post‐treatment
Youngseok Kim, Jongwon Lee, Jiwoong Kim, Jung Il Yoo, Junggeon Park, Jaeyoung Lee, Heung Cho Ko, HyungJu Ahn, Myung‐Han Yoon   +8 more
wiley   +1 more source