Results 261 to 270 of about 935,910 (334)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Threat expectancies in a VR fear conditioning paradigm follow non-linear extinction patterns but are not influenced by intolerance of uncertainty. [PDF]

Sci Rep
Grill M, Kloft M, Anhäuser S, Haberkamp A.   +3 more
europepmc   +1 more source

S···O Conformation Locks Synergistic Alkoxy Chain Engineering of NIR‐II Phototheranostic Molecules for Precision Hepatocellular Carcinoma Theranostics

Advanced Science, EarlyView.
This study introduces a synergistic S‐O conformation locking and alkoxy chain engineering strategy to enhance S‐D‐A‐D‐S molecular planarity. The engineered IR‐BTOG achieves concurrent NIR‐IIa absorption and NIR‐IIb emission, demonstrating exceptional photothermal efficiency and fluorescence quantum yield.
Gui‐long Wu, Fan Wu, Senyou Tan, Hao Xiao, Qiang Kang, Sanlin Deng, Fen liu, Jinkang Zheng, Chaoqiang Li, Guodong Chen, Qinglai Yang   +10 more
wiley   +1 more source

Co-Extinctions and Co-Compensatory Species Responses to Climate Change Moderate Ecosystem Futures. [PDF]

Glob Chang Biol
Williams TJ, Garcia CR, Godbold JA, Archambault P, Solan M.   +4 more
europepmc   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Acute 17β-Estradiol Administration Enhances Fear Extinction Memory and Alters Gut Microbiota in Female Rats. [PDF]

Biol Psychiatry Glob Open Sci
Hartsgrove CE, Walker GS, Silva KD, Nunez K, Alejos K, Joseph M, Wright JR, McMullen B, Lamendella R, Maeng LY.   +9 more
europepmc   +1 more source

Meta-surface extinction theorem: a light-microscopic observation on the interference from meta-atoms

Jiacheng Li, Pengfei Gao, Rui Yang
openalex   +1 more source

Global Diversification Rates of Ferns Across Spatial and Climatic Gradients

Advanced Science, EarlyView.
Diversification rates of fern genera across the phylogeny. Abstract Geographic patterns of diversity in any group of plants are the result of the interplay of environmental conditions and the evolutionary dynamics of the respective plant group. Here, the geographic distribution of current mean diversification rates (MDR) is explored at the genus level ...
Hong Qian, Michael Kessler, Shenhua Qian
wiley   +1 more source

Analysis of a household-scale model for the invasion of Wolbachia into a resident mosquito population. [PDF]

J Math Biol
Barlow A, Penington S, Adams B.
europepmc   +1 more source

Predicting local colonization and extinction rates of freshwater mussels based on biological traits in a case of Lake Poyang

, 2017
Rui-wen Wu, Gao Bo-yu, LAN Zhichun, Zhang Ming-hua, Ouyang Shan, Xiaoping Wu   +5 more
openalex   +2 more sources