Results 221 to 230 of about 292,514 (297)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Overfishing and climate change elevate extinction risk of endemic sharks and rays in the southwest Indian Ocean hotspot. [PDF]

PLoS One
Pollom RA, Cheok J, Pacoureau N, Gledhill KS, Kyne PM, Ebert DA, Jabado RW, Herman KB, Bennett RH, da Silva C, Fernando S, Kuguru B, Leslie RW, McCord ME, Samoilys M, Winker H, Fennessy ST, Pollock CM, Rigby CL, Dulvy NK.   +19 more
europepmc   +1 more source

Society as Reality and Construction: Decolonial Citizenship‐Making

Journal of Applied Philosophy, EarlyView.
ABSTRACT Kymlicka asks whether the Marshallian vision of society‐ and membership‐making remains relevant when thinking about possible Indigenous futures. In this article, I first respond to this question. Given the meticulousness of Kymlicka's analysis, my response should be read as complementary, offering additional considerations that I think warrant
Rauna Kuokkanen
wiley   +1 more source

Sex ratio distorting microbes exacerbate arthropod extinction risk in variable environments. [PDF]

Ecol Evol
Fisher AM, Knell RJ, Price TAR, Bonsall MB.   +3 more
europepmc   +1 more source

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

Journal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara, Carlina Leila Colussi, Lucía Magdalena Odetti, Damián Marino, María Fernanda Simoniello   +4 more
wiley   +1 more source

Population Viability Analysis on Chinese Goral Indicates an Extinction Risk for a Local Population in Beijing, China. [PDF]

Animals (Basel)
Wu R, Zhang X, Zhao J, Yi D, Gao F, Bao W.   +5 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Mechanistic trials, therapy and developmental science—An exemplar from early autism care

JCPP Advances, EarlyView.
Abstract Background Mechanistic design and analysis in clinical trials remains relatively rare in child mental health and autism, despite the considerable value that it could have in developing therapy practice and in illuminating basic science. Clinical trials themselves continue to have insufficient influence on actual clinical practice in child ...
Jonathan Green
wiley   +1 more source

Better estimates of extinction risk [PDF]

Nature, 2015
openaire   +1 more source

Decadal Changes of UV Aerosol Optical Depth in Hobart, Australia Measured With a Brewer MKIII: Relationship to Bushfire Events and Climate Indices

International Journal of Climatology, EarlyView.
Monthly average aerosol optical depth at 320 nm obtained with a Brewer MKIII spectrophotometer for Hobart, Australia (42.8806° S, 147.3250° E) over a 21‐year period. There is a linear trend of 15.4% per decade. There are 9 months when the average aerosol optical depth exceeds twice the monthly standard deviation.
Manuel Nuñez, Antonio Serrano, Peter Love, Nels Larson   +3 more
wiley   +1 more source