Results 41 to 50 of about 921,147 (300)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Rheumatoid nodules in thyroid gland parenchyma as an expression of rheumatoid arthritis: a case report

Journal of Medical Case Reports, 2019
Background The rheumatoid nodule is the most common extra-articular manifestation of rheumatoid arthritis. When present, it is readily identified in conventional hematoxylin and eosin sections.
Efthimios Sivridis, Maria Kouroupi, Michael Ioannis Koukourakis, Stella Arelaki, Nikolaos Lyratzopoulos, Alexandra Giatromanolaki   +5 more
doaj   +1 more source

A Study on the Extra-Articular Manifestations of Rheumatoid Arthritis [PDF]

, 2019
BACKGROUND AND OBJECTIVES: Rheumatoid arthritis is a common systemic inflammatory disease. Extra- articular manifestations are a common occurrence and are part of the spectrum of the disease.
Ponmozhi, G
core  

Cross-reactive rheumatoid factors inrheumatoid arthritis with extra-articular disease

, 1990
SUMMARY Rheumatoid factors (RF) have been shown to have considerable heterogeneity and bind with IgG aswell as with a variety of substances such as nuclear histone, non-histone nuclear protein, nitrophenylgroups or ssDNA.
S AOTSUKA, R YOKOHARI, M KINOSHITA
core   +1 more source

Case series : dual-energy CT in extra-articular manifestations of gout [PDF]

, 2020
Extra-articular manifestations of gout are common. The Achilles tendon is a frequently affected site, and uric acid deposition may have harmful effects on tendon structure and function.
Verstraete, Koenraad, Jans, Lennart, Huysse, Wouter, Chen, Min, De Vulder, Nando, Herregods, Nele   +5 more
core   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

SPECTRUM OF RHEUMATOID ARTHRITIS PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL IN PAKISTAN

Pakistan Armed Forces Medical Journal, 2021
Objective: To describe the demographic, clinical, serological and radiological scores in patients with rheumatoid arthritis (RA) presenting in a tertiary hospital in Pakistan. Study Design: Cross sectional study.
Muhammad khan, Muhammad Salman Mushtaq, Babur Salim, Sumera Mushtaq, Haris Gul, Saba Samreen   +5 more
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Severe myocarditis as a cause of the formation of cardiorenal syndrome in a patient with refractory rheumatoid arthritis

Научно-практическая ревматология, 2022
According to modern concepts, myocarditis is an inflammatory disease of the myocardium, diagnosed on the basis of generally accepted histological, immunological, immunohistochemical criteria.
Z. Yu. Mutovina, A. V. Gordeev, I. V. Rozanova, E. A. Galushko   +3 more
doaj   +1 more source

Triceps-sparing extra-articular step-cut olecranon osteotomy for distal humeral fractures: an anatomic study. [PDF]

, 2017
BACKGROUND This anatomic study investigated the distal humeral articular surface exposure achievable through a triceps-sparing oblique extra-articular osteotomy of the olecranon with a step-cut modification compared with the anconeus flap ...
Raniga, Sumit, Sumit Raniga, Flückiger, Remy, Beat K. Moor, Zumstein, Matthias, Moor, Beat Kaspar, Matthias A. Zumstein, Campana, Lorenzo, Remy Flueckiger, Lorenzo Campana, Flueckiger R, Campana L, Zumstein MA, Raniga S, Moor BK   +14 more
core   +1 more source