Results 281 to 290 of about 3,262,386 (333)

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Endothelial-Derived Extracellular Vesicles During Exercise in COPD Patients. [PDF]

Clin Respir J
Okpechi SC, Wyczechowska D, DeBoisblanc B, Johnson JL, Ghonim MA, Bauer N, Boulares HA, Lammi MR.   +7 more
europepmc   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Extracellular Vesicles in Sarcoma: Implications for Tumor Progression and Therapy. [PDF]

Int J Nanomedicine
Wang Y, Gao S, Zhang G, Xiao W, Xu B, Li W.   +5 more
europepmc   +1 more source

Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating

Advanced Biology, EarlyView.
This study explores how magnesium–calcium coatings on titanium promote osteogenesis by releasing ions and elevating pH during degradation. Using osteoblast‐like cells, the research demonstrates that both ion release and pH changes contribute to cell proliferation, differentiation, and mineralization, offering new insights into the design of bioactive ...
Risa Miyake, Masaya Shimabukuro, Masahiko Terauchi, Eriko Marukawa, Masakazu Kawashita   +4 more
wiley   +1 more source

Correction to "Homosalate Boosts the Release of Tumour-derived Extracellular Vesicles With Protection Against Anchorage-Loss Property". [PDF]

J Extracell Vesicles
europepmc   +1 more source

Superoxide Dismutase 3 Deficiency Disrupts the Regulation of Oxidative Stress Caused by Polystyrene Nanoplastics. [PDF]

Antioxidants (Basel)
Sim Y, Kim JH, Lee JS, Jeong J, Cho HJ.
europepmc   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Unlocking extracellular mitochondria from bench to clinical application in stroke. [PDF]

Stem Cells Transl Med
Hamanaka G, Back DB, Park JH, Ishikane S, Hayakawa K.   +4 more
europepmc   +1 more source

Astrocytic gap junction blockade markedly increases extracellular potassium without causing seizures in the mouse neocortex

, 2016
Paolo Bazzigaluppi, Iliya Weisspapir, Bojana Stefanovic, Luc Leybaert, Peter L. Carlen   +4 more
openalex   +2 more sources