Results 161 to 170 of about 1,434,762 (289)

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Potential of Indonesian Marine Endophytic Fungi as Extracellular Enzymes Producers. [PDF]

J Fungi (Basel)
Nurazizah MA, Hardiningtyas SD, Budiman MA, Kadir NHA, Tarman K.   +4 more
europepmc   +1 more source

Evaluation of in vitro activities of extracellular enzymes from Aspergillus species isolated from corneal ulcer/keratitis. [PDF]

Saudi J Biol Sci, 2020
Balakrishnan Sangeetha A, Abdel-Hadi A, Hassan AS, Shobana CS, Suresh S, Abirami B, Selvam KP, Al-Baradie RS, Banawas S, Alaidarous M, Alshehri B, Dukhyil AAB, Dhanasekaran S, Manikandan P.   +13 more
europepmc   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Novel Endophytic Fungi from <i>Euchresta tubulosa</i> Dunn: Characterization of Their Bioactive Secondary Metabolites and Extracellular Enzymes. [PDF]

Microorganisms
Yin X, Guo W, Wang Q, Nie R, Qing D, Hu Y, Hu S, Wang L, Ye X, Yao S, Cheng J.   +10 more
europepmc   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Degradation of catecholate, hydroxamate, and carboxylate model siderophores by extracellular enzymes. [PDF]

PLoS One
Chukwuma CE, Duckworth OW, Baars O.
europepmc   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

MicroRNA profile of circulating extracellular vesicles are associated with upregulation of neuroinflammatiory signalling pathway in aged animals

, 2020
Freishtat, R., Moszkowicz, Catherina Isdra, Batabyal, Rachael, Siqueira, Ionara Rodrigues, Bastos, Catherina Isdra Moszkowicz, Cechinel, Laura Reck   +5 more
core   +1 more source

Metagenomic analysis reveals genetic coupling between TonB-dependent transporters and extracellular enzymes in coastal bacterial communities. [PDF]

Mar Life Sci Technol
Liu S, Chen Q, Qiu X, Li W, Tang K.
europepmc   +1 more source