Results 231 to 240 of about 1,434,762 (289)

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Extracellular vesicles and acetylation: reciprocal regulation in disease progression. [PDF]

Front Immunol
Liu Y, Wu S, Wang Y, Zhu X, Kang L.
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Microbial Biotechnology at the Frontiers of Innovation: Engineering Solutions for Health, Industry and Sustainability. [PDF]

Microb Biotechnol
Bernal P, Ramos JL.
europepmc   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Global Hotspots and Trends in Microbial Plastic Biodegradation for Plastic Waste Management: A Mini-Review and Bibliometric Analysis. [PDF]

Microorganisms
Wang H, Guo Z, Liu Y, Shen H, Chen F, Peng M.   +5 more
europepmc   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Molecular Regulation of Biofilm Development in <i>Stenotrophomonas maltophilia</i>: Integrating Signal Transduction, Environmental Adaptation, and Antibiotic Resistance. [PDF]

Pathogens
Yu K, Zhao G, Zhang Q, Zhang X.
europepmc   +1 more source

The TG2/LRP1 Pathway for T Cell Activation by Post-Translationally Modified Antigens. [PDF]

Immunol Rev
Sewa AS, Yang FC, Khosla C.
europepmc   +1 more source

Copper, cuproptosis, and cancer: biology concepts of a novel cell death. [PDF]

Apoptosis
Eshraghi R, Hosseini N, Yazdani MS, Badihi S, Pirmoradian P, Bahrami A, Darouei B, Ghanouni S, Lam AK, Hamblin MR.   +9 more
europepmc   +1 more source