Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu +9 more
wiley +1 more source
Overcoming <i>Candida</i> biofilm resistance: targeting persister cells with probiotic-derived metabolites. [PDF]
Debta P +5 more
europepmc +1 more source
Dense Nanofibrillar Collagen–Silica Hybrids with High Strength and ECM‐Mimetic Tissue Integration
Dense nanofibrillar collagen–silica hybrids are engineered by synchronizing collagen fibrillogenesis with silica condensation, producing printable scaffolds that unexpectedly approach native extracellular matrix organization and strength. These cell‐free constructs guide endogenous cell‐infiltration, enable localized matrix remodeling, and integrate ...
Norein Norein +7 more
wiley +1 more source
Effects of VeA Gene on the Growth, Pigment and Citrinin Synthesis of Monascus ruber M7. [PDF]
Kuang L +6 more
europepmc +1 more source
3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization
Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono +6 more
wiley +1 more source
Optimization of Liquid Culture of Extracellular Flavonoids of <i>Sanghuangporus</i> and Evaluation of Antioxidant Activity of Fermentation Broth. [PDF]
Wang Y +8 more
europepmc +1 more source
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
Lignin-Carbohydrate Nano-Sized Structures: An Evidence of Intracellular Lignin Biosynthesis? [PDF]
Shutskiy NA +10 more
europepmc +1 more source
Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels
This study establishes a materials‐based design framework for polymer hydrogels in tissue clearing, linking physicochemical properties to performance in tissue processing, labeling, and imaging. By analyzing rheology, swelling, porosity, antibody diffusion, mechanical performance, and thermochemical stability across platforms, this work provides a ...
Sangjae Kim +8 more
wiley +1 more source
Bridging Osteoimmunology and Regenerative Therapy: The Role of MSCs and Extracellular Vesicles. [PDF]
Álvarez-Iglesias I +5 more
europepmc +1 more source

