Results 231 to 240 of about 247,554 (291)

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han   +10 more
wiley   +1 more source

Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

open access: gold, 2019
Victor Bodart‐Santos   +10 more
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

open access: yesAdvanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei   +10 more
wiley   +1 more source

Plant-derived extracellular vesicles in facial aesthetics. [PDF]

open access: yesExtracell Vesicles Circ Nucl Acids
Yang N, Wang Y, Liu H, Li T, Lu M, Lu R.
europepmc   +1 more source

Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes

open access: green, 2017
Andrew M. Overmiller   +11 more
openalex   +2 more sources

Dysregulation of CircZNF79(5) Modulates YBX1 Stability and Selective Autophagy to Drive Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
In HCC, circZNF79(5) binds to YBX1 and functions as an oncogene, recruits BRCC36 to remove K63‐linked ubiquitin chains to stabilize YBX1 protein, and promotes HCC progression via the HIF‐1 signaling pathway. Conversely, circZNF79(5) silencing activates the AMPK/mTOR pathway, inducing p62‐mediated selective autophagic degradation of YBX1.
Xueqiang Guo   +20 more
wiley   +1 more source

Extracellular vesicles in bone aging: therapeutic strategies and applications. [PDF]

open access: yesExtracell Vesicles Circ Nucl Acids
Tang L   +7 more
europepmc   +1 more source

Extracellular vesicles: Unraveling their physiology and role in cancer [PDF]

open access: green, 2018
Showkat Ahmad Shah   +7 more
openalex  

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