Cyclodextrin nanoparticle containing both Ga(NO3)3 and GaPP is synthesized and tested against non‐tuberculous mycobacteria (NTM). The in vivo efficacy of the nanoparticle therapy is additionally tested by treating pulmonary NTM infections in mice and observed much greater effectiveness in bacterial clearance and survival of mice.
Seoung‐ryoung Choi +2 more
wiley +1 more source
Emerging Roles of Extracellular Vesicles in the Pathogenesis, Diagnosis, and Therapy of Periodontitis. [PDF]
Fu Y, Wang M, Teng R, Li A.
europepmc +1 more source
Corpus luteum presence in the bovine ovary increase intrafollicular progesterone concentration: consequences in follicular cells gene expression and follicular fluid small extracellular vesicles miRNA contents [PDF]
Paola Maria da Silva Rosa +8 more
openalex +1 more source
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu +17 more
wiley +1 more source
Uncovering the Molecular Networks of Extracellular Vesicles in the Pathogenesis of Periodontitis. [PDF]
Yu W, Huoshen W, Zhong W, Gao X, Song J.
europepmc +1 more source
PRDM16 Reduces Cellular Senescence by Upregulating GSTM1
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan +7 more
wiley +1 more source
Plant-derived extracellular vesicles: composition, function and clinical potential. [PDF]
Huang D +10 more
europepmc +1 more source
Therapeutic Applications of Extracellular Vesicles in Inflammatory Bowel Disease [PDF]
Sang Hyun Kim +5 more
openalex +1 more source
Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
Proteolytic activities of extracellular vesicles attenuate A-synuclein aggregation. [PDF]
Vekrellis K +8 more
europepmc +1 more source

