Results 321 to 330 of about 977,542 (369)

CD63, a new therapeutical candidate for cholesterol homeostasis regulation through extracellular vesicles? [PDF]

Extracell Vesicles Circ Nucl Acids
Saint-Pol J, Fenart L.
europepmc   +1 more source

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

Advanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu, Xing Zhao, Ting Jiang, Ningjuan Ouyang, Peilin Li, Wei Yang, Zhihe Zhao   +6 more
wiley   +1 more source

Interactions with and activation of immune cells by CD41a⁺ extracellular vesicles. [PDF]

Front Immunol
Tamagne M, Khelfa M, Many S, Neyrinck-Leglantier D, Delorme AS, Pinheiro MK, Andrieu M, Cleophax S, Pirenne F, Vingert B.   +9 more
europepmc   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Small extracellular vesicles: the origins, current status, future prospects, and applications. [PDF]

Stem Cell Res Ther
Zhou X, Huang J, Zhang D, Qian Z, Zuo X, Sun Y.   +5 more
europepmc   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

Porcine jejunal-derived extracellular vesicles participate in the regulation of lipid metabolism. [PDF]

J Anim Sci Biotechnol
Fan Y, Deng H, Zhu J, Luo J, Chen T, Sun J, Zhang Y, Xi Q.   +7 more
europepmc   +1 more source

Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS‐Induced Depressive‐Like Behaviors

Advanced Science, EarlyView.
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao, Zhongkun Zhang, Minzi Ju, Liang Bian, Huijuan Wang, Sibo Zhao, Ningbo Cai, Yu Wang, Yanpeng Jia, Ling Shen, Yuan Zhang, Honghong Yao   +11 more
wiley   +1 more source

Harnessing Extracellular Vesicles for Targeted Drug Delivery in Ovarian Cancer. [PDF]

Pharmaceutics
Yun JH, Noh YR, Yoo S, Park S, Choi Y, An J, Kim I.   +6 more
europepmc   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source