Results 141 to 150 of about 40,665 (195)

Quantitative assessment reveals the dominance of duplicated sequences in germline-derived extrachromosomal circular DNA

open access: hybrid, 2021
Lila Mouakkad   +9 more
openalex   +1 more source

Innovative insights into extrachromosomal circular DNAs in gynecologic tumors and reproduction [PDF]

open access: diamond, 2023
Ning Wu   +7 more
openalex   +1 more source

A Guide to Extrachromosomal DNA: Cancer’s Dynamic Circular Genome

open access: yesCancer Discovery
Abstract Focal amplifications of oncogenes are important cancer drivers. They can occur on chromosomes or in the context of circular extrachromosomal DNA (ecDNA). Many key features of ecDNAs were described in the 1960s to 1980s, including their “unstable” nature and their ability to confer drug ...
Natasha E. Weiser   +3 more
openaire   +2 more sources

A standardized protocol for sample preparation for scanning electron microscopy to visualize extrachromosomal DNA

open access: yesBioTechniques
Extrachromosomal DNA (ecDNA) are circular DNA structures associated with cancer and drug resistance. One specific type, double minute (DM) chromosomes, has been studied since the 1960s using imaging techniques like cytogenetics and fluorescence ...
Jillann A. Madren   +5 more
doaj   +1 more source

Methods for the purification and detection of single nucleotide KRAS mutations on extrachromosomal circular DNA in human plasma [PDF]

open access: gold, 2023
Lasse Bøllehuus Hansen   +8 more
openalex   +1 more source

Extrachromosomal DNA : New Players in Oncology

open access: yesAsian Journal of Medical Sciences
DNA that is found outside the main chromosomes in a cell's nucleus is known as extrachromosomal DNA. This type of DNA is not part of the standard 23 pairs of chromosomes in humans and instead exists as standalone circular or linear DNA structures. Unlike
Ruby Dhar   +2 more
doaj   +1 more source

Cir-DNA Sequencing Revealed the Landscape of Extrachromosomal Circular DNA in Articular Cartilage and the Potential Roles in Osteoarthritis [PDF]

open access: hybrid, 2023
Wei Xiang   +13 more
openalex   +1 more source

cir-DNA sequencing revealed the landscape of extrachromosomal circular DNA in articular cartilage and the potential roles in osteoarthritis

open access: green, 2022
Wei Xiang   +13 more
openalex   +1 more source

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