Extrachromosomal circular dna - Open Access .click

Cytogenetic and Genome Research
Background: Extrachromosomal circular DNA (eccDNA) has emerged as a central focus in molecular biology, with various types being found across species through advanced techniques, including high-throughput sequencing.
Yali Peng +7 more
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Gene amplifications and extrachromosomal circular DNAs: function and biogenesis

Molecular Biology Reports, 2023
Gene amplification is an increase in the copy number of restricted chromosomal segments that contain gene(s) and frequently results in the over-expression of the corresponding gene(s). Amplification may be found in the form of extrachromosomal circular DNAs (eccDNAs) or as linear repetitive amplicon regions that are integrated into chromosomes, which ...
Ali Yüksel, Oğuz Altungöz
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Extrachromosomal Circular DNA and Aging Cells

1985
A DNA sequence situated in the human genome between Alu-repeat clusters ("Inter-Alu" DNA) is progressively amplified in extrachromosomal DNA, including covalently closed DNA circles, during serial passage of diploid fibroblasts. A single size-class of Inter-Alu circles is also amplified in lymphocytes from 16 of 24 old donors and yet is not detected in
Karl T. Riabowol +5 more
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Extrachromosomal circular DNA landscape of breast cancer with lymph node metastasis

International Journal of Cancer
Breast cancer (BC) is a complex disease with diverse manifestations, often resulting in lymph node metastasis (LNM) and impacting patient prognosis. Extrachromosomal circular DNA (eccDNA) has emerged as a key player in tumorigenesis, yet its contribution
Yuhan Bao +6 more
semanticscholar +1 more source

medicine
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