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Extrachromosomal circular DNA elements in human gouty inflammatory
2022Gout is an autoinflammatory disease caused by the deposition of monosodium urate (MSU) crystals in tissues and joints, and it is now the most common inflammatory arthritis. The epidemiology worldwide shows an increase in incidence and prevalence in both developed and developing countries.
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Extrachromosomal circular DNAs and genomic sequence plasticity in eukaryotic cells
Mutation Research/DNAging, 1990The ability of eukaryotic organisms of the same genotype to vary in developmental pattern or in phenotype according to varying environmental conditions is frequently associated with changes in extrachromosomal circular DNA (eccDNA) sequences. Although variable in size, sequence complexity, and copy number, the best characterized of these eccDNAs ...
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EXTRACHROMOSOMAL CIRCULAR DNA IN MALE GERMLINE CELLS
Fertility and Sterility, 2023Melanie Evans +4 more
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Exploring the Role of Extrachromosomal Circular DNA in Human Diseases
Cytogenetic and Genome ResearchBackground: Extrachromosomal circular DNA (eccDNA) has emerged as a central focus in molecular biology, with various types being found across species through advanced techniques, including high-throughput sequencing. This dynamic molecule exerts a significant influence on aging and immune function and plays pivotal roles in autoimmune diseases, type 2 ...
Yali, Peng +7 more
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Global characterization of extrachromosomal circular DNAs in four body fluids
International Journal of Legal MedicineDetermination of the type of body fluids is highly desired in forensic investigations. Extrachromosomal circular DNA (eccDNA) is a double-stranded, circular type of nucleic acid molecule that exists outside chromosomes and is ubiquitous in eukaryotic cells, which is widely explored in clinical research.
Lanrui, Jiang +12 more
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Chemical recycling to monomer for an ideal, circular polymer economy
Nature Reviews Materials, 2020Geoffrey W Coates, Yutan D Y L Getzler
exaly
The expanding regulatory mechanisms and cellular functions of circular RNAs
Nature Reviews Molecular Cell Biology, 2020Ling-Ling Chen
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New frontiers in enzyme immobilisation: robust biocatalysts for a circular bio-based economy
Chemical Society Reviews, 2021Roger Arthur Sheldon, Dean Brady
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