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SCALING DETECTION IN EXTRACHROMOSOMAL DNA
Fractals, 2022In this work, we study the statistical correlations in mitochondrial and chloroplastid genomes using the diffusion entropy analysis method and estimate the value of the Hurst exponent using the detrended fluctuation analysis.
S. Jaroszewicz +3 more
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Extrachromosomal DNA in cancer
Nature Reviews CancerExtrachromosomal DNA (ecDNA) has recently been recognized as a major contributor to cancer pathogenesis that is identified in most cancer types and is associated with poor outcomes. When it was discovered over 60 years ago, ecDNA was considered to be rare, and its impact on tumour biology was not well understood.
Xiaowei Yan, P. Mischel, Howard Y. Chang
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Extrachromosomal DNA (ecDNA) in cancer pathogenesis.
Current Opinion in Genetics & Development, 2021In cancer, oncogenes and surrounding regulatory regions can untether themselves from chromosomes, forming extrachromosomal DNA particles (ecDNAs). Because of their non-chromosomal inheritance, ecDNA drives high oncogene copy number and intratumoral genetic heterogeneity, endowing tumors with the ability to rapidly change their genomes, accelerating ...
Sihan Wu, V. Bafna, P. Mischel
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Extrachromosomal DNA in eucaryotes
Plasmid, 1985Eucaryotic extrachromosomal DNAs have been organized into four major classes: (1) Organelle DNAs, (2) plasmid DNAs, (3) amplified genes, and (4) intermediates and/or by-products of DNA transpositions and rearrangements. In this review some of the relatively well-characterized members of each class are described; it is suggested that many of them ...
M G, Rush, R, Misra
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Extrachromosomal DNA of Mycoplasma hominis
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973Abstract An extrachromosomal circular duplex DNA has been isolated from Mycoplasma hominis. This plasmid DNA has a molecular weight of about 17.8 · 106, a buoyant density of 1.680 g/ml and appears to be unrelated to the similar sized Staphylococcus aureus penicillinase plasmids.
D, Zouzias +3 more
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Extrachromosomal DNA-mediated glyphosate resistance in Italian ryegrass.
Pest Management Science, 2023BACKGROUND A Italian ryegrass population from Arkansas, USA developed glyphosate resistance due to EPSPS gene amplification. The plants in this population with ~70 EPSPS copies were used in the present study for the physical mapping of amplified copies ...
D. Koo +7 more
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Extrachromosomal DNA in Bacteria
Angewandte Chemie International Edition in English, 1973AbstractIn addition to chromosomal DNA carrying the genetic information of the cell, many bacterial cells contain smaller circular DNA factors known as plasmids or episomes. These genetic elements endow the cell with additional biochemical capabilities.
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