EccDNA-Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation. [PDF]
Shi B+12 more
europepmc +1 more source
Machine learning-based extrachromosomal DNA identification in large-scale cohorts reveals its clinical implications in cancer. [PDF]
Wang S+10 more
europepmc +1 more source
Intratumoral heterogeneity and drug resistance in cancer. [PDF]
Fu YC, Liang SB, Luo M, Wang XP.
europepmc +1 more source
Perspectives of RNAi, CUADb and CRISPR/Cas as Innovative Antisense Technologies for Insect Pest Control: From Discovery to Practice. [PDF]
Kumar H+8 more
europepmc +1 more source
Innovative insights into extrachromosomal circular DNAs in gynecologic tumors and reproduction. [PDF]
Wu N+7 more
europepmc +1 more source
Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors. [PDF]
van Belzen IAEM+19 more
europepmc +1 more source
Extrachromosomal inheritance in Schizosaccharomyces pombe [PDF]
In contrast to the wild-type, mutant [ANTr8] is able spontaneously to throw off stable respiratory deficient mutants. The frequency of these mutants is considerably enhanced by treatment with ethidium bromide (EB) or the azo-dye Janus green (JG). An unstable cell state with a petite-like phenotype is found in both mutant [ANTr8] and wild-type after EB ...
Klaus Wolf+3 more
semanticscholar +9 more sources
Extrachromosomal inheritance in Schizosaccharomyces pombe [PDF]
In the antimycin--resistant mutant anar-8 of the fission yeast Schizosaccharomyces pombe (Sch.p.) spontaneous mutants were isolated showing high resistance to the aminoglycoside antibiotic paromomycin. All mutants were resistant to the structurally related antibiotic neomycin.
G. Seitz+5 more
semanticscholar +10 more sources
The Role of Extrachromosomal Inheritance in Plant Breeding
Publisher Summary This chapter discusses several mechanisms involved in extrachromosomal inheritance. It is demonstrated that chloroplasts and mitochondria contain their own deoxyribonucleic acid (DNA), with a unique informational content. Consequently, it seems reasonable to assume that many cases of extrachromosomal inheritance involve the genetic ...
Paul Harvey+2 more
semanticscholar +4 more sources
Extrachromosomal inheritance in Schizosaccharomyces pombe
Crosses involving mitochondrial markers conferring resistance to antimycin (anar, AR), chloramphenicol (capr, CR), and erythromycin (eryr, ER) in cis- and trans-configuration were studied by zygote clone analysis. Mutant anar-8, from which all other drug--resistant isolates were derived, exhibits a highly biased transmission (6.8% anar) in an analysis ...
G. Seitz-Mayr, K. Wolf, F. Kaudewitz
semanticscholar +10 more sources