Results 51 to 60 of about 208,275 (346)

CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure. [PDF]

, 2006
BACKGROUND: An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma, volutrauma and oxygen toxicity can prevent lung ...
Clemens, Felicity, Elbourne, Diana, Firmin, Richard, Hardy, Pollyanna, Hibbert, Clare, Killer, Hilliary, Mugford, Miranda, Peek, Giles J, Thalanany, Mariamma, Tiruvoipati, Ravin, Truesdale, Ann, Wilson, Andrew   +11 more
core   +3 more sources

Extracorporeal Photopheresis—An Overview

Frontiers in Medicine, 2018
Extracorporeal photopheresis (ECP) has been in clinical use for over three decades after receiving FDA approval for the palliative treatment of the Sézary Syndrome variant of cutaneous T-cell lymphoma (CTCL) in 1988. After the first positive experiences with CTCL, additional indications have been successfully explored including areas such as graft-vs ...
Christian Jantschitsch, Ara Cho, Robert Knobler   +2 more
openaire   +4 more sources

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Hammer, C., Heil, W., Lemmens, H.-P., Matthes, M., Neuhaus, P., Padval, D., Puhl, G., Schön, M. R.   +7 more
core   +1 more source

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

Advanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin, Jose Crugeiras, Chiara Bisquoli, Davide Barboni, Martina Catani, Bruno Rodríguez‐Meana, Rita Boaretto, Michele Albicini, Stefano Caramori, Claudio Trapella, Thomas Stieglitz, Yara Baslan, Hanna Karlsson‐Fernberg, Fernanda L. Narvaez‐Chicaiza, Edoardo Marchini, Alberto Cavazzini, Ruben López‐Vales, Maria Asplund, Xavier Navarro, Stefano Carli   +19 more
wiley   +1 more source

Extracorporeal Organ Support for Burn-Injured Patients

European Burn Journal
As mortality relating to severe acute burn injury improves, patients are surviving longer into the critical care phase, which is commonly complicated by multisystem organ failure.
Garrett W. Britton, Amanda R. Keith, Barret J. Halgas, Joshua M. Boster, Nicholas S. Niazi, Kevin K. Chung, Leopoldo C. Cancio   +6 more
doaj   +1 more source

Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): update and insights into current practices and future directions for research and implementation

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background In this review, we assess the state of Resuscitative Endovascular Occlusion of the Aorta (REBOA) today with respect to out-of-hospital (OOH) vs. inhospital (H) use in blunt and penetrating trauma, as well as discuss areas of promising research
Marianne A. Thrailkill, Kevin H. Gladin, Catherine R. Thorpe, Teryn R. Roberts, Jae H. Choi, Kevin K. Chung, Corina N. Necsoiu, Todd E. Rasmussen, Leopoldo C. Cancio, Andriy I. Batchinsky   +9 more
doaj   +1 more source

Rituximab induced pulmonary edema managed with extracorporeal life support [PDF]

, 2018
Though rare, rituximab has been reported to induce severe pulmonary edema. We describe the first report of ECLS utilization for this indication. A 31-year-old female with severe thrombotic thrombocytopenic purpura developed florid pulmonary edema after ...
Aguilar, Patrick, Balsara, Keki R, Isakow, Warren, Itoh, Akinobu, Masood, Muhammad F, Miller, Jacob R, Sanfilippo, Kristen M   +6 more
core   +3 more sources

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Combination of Polydopamine and Plasma Oxidation to Increase Tissue Integration of Polyurethane‐Silicone Copolymers for Cardiovascular Implants

Advanced Healthcare Materials, EarlyView.
Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong, Jennifer M. Dyson, Lingxiao Zeng, Saeedreza Zeibi Shirejini, John S. Forsythe, Shaun D. Gregory   +5 more
wiley   +1 more source