Results 31 to 40 of about 725,174 (193)
CytoSorb in patients with coronavirus disease 2019: A rapid evidence review and meta-analysis
BackgroundAfter its approval by the European Union in 2011, CytoSorb therapy has been applied to control cytokine storm and lower the increased levels of cytokines and other inflammatory mediators in blood.
Shilin Wei +13 more
doaj +1 more source
ObjectiveTo examine associations between temperature-related indicators and incident cardiovascular-kidney-metabolic (CKM) multimorbidity in middle-aged and older Chinese adults.MethodsWe analyzed 4,665 CKM-free participants from the China Health and ...
JiaXin Huang +3 more
doaj +1 more source
Objective: Previous studies have suggested that transpulmonary thermodilution (TPTD) measurements are influenced by extracorporeal circulation methods, such as blood purification.
Toshikazu Sakai +13 more
doaj +1 more source
Objective To explore the factors affecting patient outcomes in pulmonary artery thromboendarterectomy (PTE) under deep hypothermic circulatory arrest (DHCA) and cardiopulmonary bypass (CPB) support and to provide a reference for further improving the ...
Ming Guan +4 more
doaj +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Gut microbiota and metabolites in acute lung injury: mechanisms and therapeutic perspectives
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), represent a clinical syndrome with high mortality, characterized by excessive pulmonary inflammation and oxidative stress.
Shuyuan Yi +8 more
doaj +1 more source
Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir +3 more
wiley +1 more source
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a severe respiratory condition associated with elevated morbidity and mortality. Understanding their complex pathophysiological mechanisms is crucial for developing new preventive and ...
Lan Luo +9 more
doaj +1 more source
ObjectiveTo summarize our center's experience with cardiopulmonary bypass (CPB) management in 21 neonates with critical congenital heart disease (CCHD) who underwent immediate postpartum cardiac surgery, and to report their early clinical outcomes ...
Jialu Wang +4 more
doaj +1 more source
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò +7 more
wiley +1 more source

