Results 31 to 40 of about 725,174 (193)

CytoSorb in patients with coronavirus disease 2019: A rapid evidence review and meta-analysis

open access: yesFrontiers in Immunology, 2023
BackgroundAfter its approval by the European Union in 2011, CytoSorb therapy has been applied to control cytokine storm and lower the increased levels of cytokines and other inflammatory mediators in blood.
Shilin Wei   +13 more
doaj   +1 more source

Temperature-related indicators and risk of incident cardiovascular-kidney-metabolic multimorbidity in middle-aged and older adults: a longitudinal cohort study from CHARLS

open access: yesFrontiers in Public Health
ObjectiveTo examine associations between temperature-related indicators and incident cardiovascular-kidney-metabolic (CKM) multimorbidity in middle-aged and older Chinese adults.MethodsWe analyzed 4,665 CKM-free participants from the China Health and ...
JiaXin Huang   +3 more
doaj   +1 more source

The influence of extracorporeal circulation on EV1000 monitor hemodynamic parameters at two sites of intravenous cold saline injection

open access: yesFujita Medical Journal, 2016
Objective: Previous studies have suggested that transpulmonary thermodilution (TPTD) measurements are influenced by extracorporeal circulation methods, such as blood purification.
Toshikazu Sakai   +13 more
doaj   +1 more source

Factors affecting patient outcomes in pulmonary artery thromboendarterectomy under deep hypothermic circulatory arrest and cardiopulmonary bypass support----a single center’s experience

open access: yesBMC Cardiovascular Disorders
Objective To explore the factors affecting patient outcomes in pulmonary artery thromboendarterectomy (PTE) under deep hypothermic circulatory arrest (DHCA) and cardiopulmonary bypass (CPB) support and to provide a reference for further improving the ...
Ming Guan   +4 more
doaj   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

open access: yesAdvanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi   +6 more
wiley   +1 more source

Gut microbiota and metabolites in acute lung injury: mechanisms and therapeutic perspectives

open access: yesRespiratory Research
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), represent a clinical syndrome with high mortality, characterized by excessive pulmonary inflammation and oxidative stress.
Shuyuan Yi   +8 more
doaj   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

open access: yesAdvanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir   +3 more
wiley   +1 more source

The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome

open access: yesClinical and Translational Medicine
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a severe respiratory condition associated with elevated morbidity and mortality. Understanding their complex pathophysiological mechanisms is crucial for developing new preventive and ...
Lan Luo   +9 more
doaj   +1 more source

Immediate postpartum cardiac surgery for critical congenital heart disease: cardiopulmonary bypass management and early outcomes in 21 neonates

open access: yesFrontiers in Cardiovascular Medicine
ObjectiveTo summarize our center's experience with cardiopulmonary bypass (CPB) management in 21 neonates with critical congenital heart disease (CCHD) who underwent immediate postpartum cardiac surgery, and to report their early clinical outcomes ...
Jialu Wang   +4 more
doaj   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

open access: yesAdvanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò   +7 more
wiley   +1 more source

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