Pre-transplant infusion of donor leukocytes treated with extracorporeal photochemotherapy induces immune hypo-responsiveness and long-term allograft survival in murine models [PDF]
Scientific Reports, 2022 Recipients of solid organ transplantation (SOT) rely on life-long immunosuppression (IS), which is associated with significant side effects. Extracorporeal photochemotherapy (ECP) is a safe, existing cellular therapy used to treat transplant rejection by
Jennifer Schneiderman +13 more
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Alʹmanah Kliničeskoj Mediciny, 2016 The article describes treatment experience with a tumor stage of mycosis fungoides patient treated with extracorporeal photochemotherapy that showed high clinical efficacy. The patient responded with significant regression of the skin elements after two
V. A. Molochkov +2 more
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THE VALUE OF EXTRACORPOREAL PHOTOCHEMOTHERAPY IN RENAL TRANSPLANT REJECTION INHIBITION
Вестник трансплантологии и искусственных органов, 2016 The aim of the study was to determine the value of extracorporeal photochemotherapy (EPCT) in the induction of tissue tolerance in renal transplantation.
V. A. Fedulkina +4 more
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Extracorporeal photochemotherapy for generalized deep morphea. [PDF]
Arch Dermatol, 2009 Morphea, or localized scleroderma, can at times constitute a severely disabling and aggressive disease with no single therapy proven to be curative or the standard of care. Herein, we report the case of a patient with severe disabling generalized deep morphea who showed a marked clinical response to treatment with extracorporeal photochemotherapy (ECP).
Neustadter JH +3 more
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EXTRACORPOREAL PHOTOCHEMOTHERAPY IN PSORIASIS AND PSORIATIC ARTHRITIS
Alʹmanah Kliničeskoj Mediciny, 2016 Background: Psoriasis is the most prevalent chronic dermatosis of an autoimmune origin that is characterized by increasing incidence of both severe clinical forms and complications, the most threatening of which is psoriatic arthritis.
E. S. Yakubovskaya +3 more
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Targeting of T/Tn antigens with a plant lectin to kill human leukemia cells by photochemotherapy. [PDF]
PLoS ONE, 2011 Photochemotherapy is used both for solid tumors and in extracorporeal treatment of various hematologic disorders. Nevertheless, its development in oncology remains limited, because of the low selectivity of photosensitizers (PS) towards human tumor cells.
Guillaume Poiroux +11 more
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Extracorporeal photochemotherapy induces bona fide immunogenic cell death. [PDF]
Cell Death Dis, 2019 AbstractExtracorporeal photochemotherapy (ECP) is employed for the management of cutaneous T cell lymphoma (CTCL). ECP involves the extracorporeal exposure of white blood cells (WBCs) to a photosensitizer, 8-methoxypsoralen (8-MOP), in the context of ultraviolet A (UVA) radiation, followed by WBC reinfusion.
Tatsuno K +10 more
europepmc +4 more sources
SOME OF THE MECHANISMS OF EXTRACORPOREAL PHOTOCHEMOTHERAPY IN SOLID ORGAN TRANSPLANTATION
Вестник трансплантологии и искусственных органов, 2014 Reducing the risk of kidney transplant rejection is a perspective trend in modern medical science. One of the promising methods for reducing the activity of immune conflict between the recipient and the donor organ and the achievement of partial ...
A. V. Vatazin +4 more
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Current Clinical Applications of Extracorporeal Photochemotherapy [PDF]
Therapeutic Apheresis and Dialysis, 2014 AbstractFrom the 1980s, extracorporeal photochemotherapy (ECP) has been shown to be effective in a variety of pathological conditions such as erythrodermic cutaneous T‐cell lymphoma, autoimmune diseases, solid organ allograft rejection and graft versus host disease.
Maria Capuano +8 more
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Extracorporeal photochemotherapy and methotrexate in the treatment of atypical oral lichen planus
Alʹmanah Kliničeskoj Mediciny, 2018 Background: Some authors have successfully used methotrexate in the treatment of atypical oral lichen planus (LP) and noted its good tolerability.
A. V. Molochkov +3 more
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