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Miscellaneous indications for extracorporeal photochemotherapy (ECP)

Transfusion and Apheresis Science, 2014
Extracorporeal photochemotherapy (ECP) has been applied to many T-cell mediated diseases where immunosuppressive drugs are insufficient or not tolerated. As ECP is mainly used in rare indications after failure of other therapies, controlled studies are hardly possible.
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Extracorporeal Photochemotherapy: A Treatment for Organ Graft Rejection

Therapeutic Apheresis, 1997
Abstract: Extracorporeal photochemotherapy (ECPC) has been investigated experimentally and in clinical conditions in transplant rejection treatment and prevention. Repeated injections of photochemically modified syngeneic alloreactive T cells prior to transplant significantly delay rejection in a mouse skin graft model as well as in a heterotopic ...
A. Achkar   +6 more
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Extracorporeal photochemotherapy for the treatment of refractory Crohn’s disease

Transfusion and Apheresis Science, 2007
Crohn's disease is an idiopathic, relapsing inflammatory disorder of the gastrointestinal tract. We prospectively evaluated the use of extracorporeal photochemotherapy (ECP; photopheresis), an immunomodulatory therapy, to treat moderate or severe Crohn's disease (Crohn's Disease Activity Index [CDAI] score > or = 220 points) in 2 patients who failed ...
Mark Palangio   +3 more
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Treatment of Adult T Cell Leukaemia by Extracorporeal Photochemotherapy

Leukemia & Lymphoma, 1990
Four patients with chronic or smouldering type adult T cell leukaemia (ATL) were treated by extracorporeal photochemotherapy (photopheresis). From 4 to 8 months after starting photo-pheresis, skin lesions with ATL cell infiltration began to disappear. Cell surface markers in three patients showed improvement.
Kazunari Yamaguchi   +7 more
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Severe Pemphigus Foliaceus Treated With Extracorporeal Photochemotherapy

Archives of Dermatology, 1997
REPORT OF A CASE A 64-year-old man presented with a 3-year history of severe pemphigus foliaceus. He had been treated with adequate doses of systemic corticosteroids, azathioprine sodium, intermittent methotrexate sodium, and cyclosporine. Maintenance treatment with prednisone (dose range, 40-60 mg/d) and azathioprine sodium (100 mg/d) was necessary ...
José Manuel Azaña   +4 more
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Extracorporeal Photochemotherapy in Systemic Sclerosis and Severe Morphea

Dermatology, 1995
Extracorporeal photochemotherapy (EP) is a new immune-modulating therapy which combines cytapheresis and extracorporeal irradiation of leukocytes by UVA. Recently, patients with systemic sclerosis (SS) have been treated by this method, but the efficacy of EP is still controversial.Our purpose was to evaluate the efficacy and safety of EP in SS and in ...
Bernard Cribier   +4 more
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Lymphomatoid papulosis treated with extracorporeal photochemotherapy.

Oncology Reports, 1998
Lymphomatoid papulosis (LP) is a rare low-grade T-cell lymphoma which may respond to cytotoxic drugs and PUVA irradiation but long-term remission has not been achieved. Extracorporeal photochemotherapy (ECP) is an immunomodulating therapy used successfully for several types of CTCL, no experience with LP has been reported yet.
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Extracorporeal photochemotherapy for chronic erosive lichen planus

The Lancet, 1998
Topical steroids and retinoic acid are usually ineffective in the treatment of chronic erosive lichen planus (CELP). Improvement with griseofulvin and dapsone has been reported; topical cyclosporin may also help, but only 30% of patients remain improved after 1 year. We noticed that extracorporeal photochemotherapy (ECP) improved the generalised lichen
P.-A. Becherel   +5 more
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Extracorporeal photochemotherapy for treatmentof acute and chronic GVHD in childhood

Transfusion, 2001
BACKGROUND: Extracorporeal photochemotherapy (EPC) has recently been proposed for the treatment of adults with either acute or chronic GVHD. However, data on children given this therapy are scarce. A Phase I‐II study was carried out on EPC in children experiencing GVHD after allogeneic transplantation of HPCs.STUDY DESIGN AND METHODS: Nine patients ...
Salvaneschi L.   +10 more
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Treatment of refractory epidermolysis bullosa acquisita with extracorporeal photochemotherapy

British Journal of Dermatology, 1997
Treatment of epidermolysis bullosa acquisita (EBA) with conventional therapy frequently does not result in improvement. Extracorporeal photochemotherapy (ECP) is a novel immunomodulating technique which might be of benefit in the treatment of autoimmune disease. We prospectively studied three patients with refractory EBA who were treated with ECP.
Lawrence S. Chan   +2 more
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