Results 31 to 40 of about 2,322,250 (249)

Biological potential of Lophosoria quadripinnata fern extract: integration of UHPLC/ESI/QToF/MS analysis, antioxidant activity, molecular docking and molecular dynamics simulation

open access: yesFrontiers in Pharmacology
Lophosoria quadripinnata (J.F.Gmel.) C.Chr., a fern species from the Dicksoniaceae family, is widely distributed in Central and South America. This study aimed to identify the bioactive compounds in the aqueous extract of L.
Alfredo Torres-Benítez   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

How To Use Essential CBD Extract Oil ?

open access: yes, 2021
Essential CBD Extract Oil is an amazing product, with tons of applications for our everyday life. One use that is growing in popularity is for pain relief.
Essential CBD Extract, Essential CBD Extract Oil, Essential CBD Extract Reviews, Essential CBD Extract Price, Essential CBD Extract Ingredients
core   +1 more source

Cold and hot tumors: immunological determinants, cancer-immunity cycle dysregulation, and nanotechnology-driven therapeutic approaches

open access: yesMolecular Biomedicine
Cancer remains a major global health burden and the second leading cause of mortality worldwide. Recent advances in cancer immunotherapy have emphasized the critical role of the tumor microenvironment (TME) in determining therapeutic outcomes, leading to
Mohammed S. Teiama   +4 more
doaj   +1 more source

Effects of Dietary Inclusion of Saccharina latissima and Ulva lactuca on Growth Performance and Gut Health in Growing Rabbits

open access: yesAgriculture
Rabbit meat production faces challenges due to the prevalence of gastrointestinal diseases in rabbits, exacerbated by restrictions on antibiotic use in European animal production.
Sabela Al-Soufi   +10 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Evaluation of anti-inflammatory, anti-nociceptive, and anti-pyretic potential of hydroalcoholic extract of Trifolium pratense in mice

open access: yesComplementary Medicine Journal of Faculty of Nursing and Midwifery, 2019
Introduction: There are some reports in traditional medicine concerning the anti-inflammatory, anti-nociceptive and anti-pyretic effects of Trifolium pretense (red clover).
Parandin R
doaj  

Chokeberry Products and By-Products as the Potential Pharmaceuticals for Kidney Protection—An Experimental Study in Rats

open access: yesPlants
The study aimed to investigate the protective effects of chokeberry fruit products and by-products against cisplatin-induced acute nephrotoxicity in rats.
Milica Milutinović   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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