Results 111 to 120 of about 6,935,481 (374)

Methodology of inclusions removing from steel flowing through the tundish

open access: yesMetalurgija, 2017
Obtaining high quality steels mainly depends on the quantity of non-metallic inclusions contained into it and this, in turn, to a large extent on the structure of the flow in the tundish. Optimization of the flow of liquid steel through the tundish makes
M. Warzecha   +4 more
doaj  

The changes of intestinal flora and metabolites in atopic dermatitis mice

open access: yesFrontiers in Microbiology
IntroductionAtopic dermatitis (AD) is an allergic disease caused by various factors that can affect an individual’s appearance and cause psychological stress.
Feifei Wang   +7 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Volume-Enclosing Surface Extraction

open access: yes, 2012
In this paper we present a new method, which allows for the construction of triangular isosurfaces from three-dimensional data sets, such as 3D image data and/or numerical simulation data that are based on regularly shaped, cubic lattices.
B.R. Schlei   +25 more
core   +1 more source

para-Menthane as a Stable Terpene Derived from Orange By-Products as a Novel Solvent for Green Extraction and Solubilization of Natural Substances

open access: yesMolecules, 2019
This study aims at investigating p-menthane, a novel bio-based solvent resulting from the hydrogenation of d-limonene, as a green alternative to n-hexane or toluene for the extraction and solubilization of natural substances.
Sara Madji   +6 more
doaj   +1 more source

Neural Relation Extraction with Selective Attention over Instances

open access: yesAnnual Meeting of the Association for Computational Linguistics, 2016
Distant supervised relation extraction has been widely used to find novel relational facts from text. However, distant supervision inevitably accompanies with the wrong labelling problem, and these noisy data will substantially hurt the performance of ...
Yankai Lin   +4 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Data Reduction Pipeline for the CHARIS Integral-Field Spectrograph I: Detector Readout Calibration and Data Cube Extraction [PDF]

open access: yes, 2017
We present the data reduction pipeline for CHARIS, a high-contrast integral-field spectrograph for the Subaru Telescope. The pipeline constructs a ramp from the raw reads using the measured nonlinear pixel response, and reconstructs the data cube using ...
Brandt, Timothy D.   +16 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Semi-Supervised Recurrent Neural Network for Adverse Drug Reaction mention extraction

open access: yesBMC Bioinformatics, 2018
Background Social media is a useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance.
Shashank Gupta   +4 more
doaj   +1 more source

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