Results 111 to 120 of about 4,381,412 (314)
J. Mehta, P. Shah, T. Mirza
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Automating Metadata Extraction: Genre Classification [PDF]
A problem that frequently arises in the management and integration of scientific data is the lack of context and semantics that would link data encoded in disparate ways.
Kim, Dr Yunhyong, Ross, Seamus
core
On Using Physical Analogies for Feature and Shape Extraction in Computer Vision
There is a rich literature of approaches to image feature extraction in computer vision. Many sophisticated approaches exist for low- and high-level feature extraction but can be complex to implement with parameter choice guided by experimentation, but ...
Hurley, David +7 more
core +1 more source
To Extract, or not to Extract: That is the Question
Aysenur Ekizler +5 more
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Recent Advances in Processing Technologies for Substance Extraction, Separation, and Enrichment
The aim of this reprint is to expound upon the latest extraction technologies in the separation of different substances from various resources for a broad range of application.
core +1 more source
Fast robust automated brain extraction
Stephen M. Smith
semanticscholar +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

