Results 141 to 150 of about 6,935,481 (374)

Integrating existing natural language processing tools for medication extraction from discharge summaries [PDF]

, 2010
Son Doan, Lisa Bastarache, Sergio Klimkowski, Joshua C. Denny, Hua Xu   +4 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nonparametric Feature Extraction from Dendrograms

, 2019
We propose feature extraction from dendrograms in a nonparametric way. The Minimax distance measures correspond to building a dendrogram with single linkage criterion, with defining specific forms of a level function and a distance function over that ...
Chehreghani, Morteza Haghir, Chehreghani, Mostafa Haghir   +1 more
core  

Coupled CFD-FEM analysis of the damage causes of the retention bunker: a case study at hard coal mine

Scientific Reports
Underground coal storage bunkers serve as crucial infrastructural components in the coal mining industry, providing secure and accessible locations for the storage of mined coal.
Tomasz Janoszek, Marek Rotkegel
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Reed canary grass cultivation mitigates greenhouse gas emissions from abandoned peat extraction areas [PDF]

, 2011
Ülo Mander, Järvi Järveoja, Martin Maddison, Kaido Soosaar, R. Aavola, Ivika Ostonen, Jüri‐Ott Salm   +6 more
openalex   +1 more source

Fast robust automated brain extraction

Human Brain Mapping, 2002
Stephen M. Smith
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Molecularly imprinted polymer microspheres for solid‐phase extraction of protocatechuic acid in Rhizoma homalomenae [PDF]

, 2011
Fangfang Chen, Guoying Wang, Yan‐Ping Shi   +2 more
openalex   +1 more source

Anthocyanin Extraction Method and Sample Preparation Affect Anthocyanin Yield of Strawberries

, 2022
Toktam Taghavi, Hiral Patel, Reza Rafie
openalex   +1 more source