Results 61 to 70 of about 2,161,452 (268)
Frontiers in PharmacologyIntroductionThe root of Paeonia suffruticosa Andrews (P. suffruticosa Andr.), is a traditional Chinese medicine. Numerous studies have shown that it possesses anti-inflammatory, antioxidant, and anti-aging effects due to its rich content of bioactive ...
Junxi Liu +16 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Imidazoline-Based Fatty Acid Derivatives as Novel Shale Inhibitors for Water-Based Drilling Fluids
Applied SciencesWater-based drilling fluids (WBMs) are widely applied in petroleum engineering due to their lower cost and reduced environmental impact compared to oil-based muds.
Ioana Gabriela Stan +8 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The interplay between epidermal cells and the cutaneous sensory nervous: a systematic review
Frontiers in ImmunologyThe skin is the largest sensory organ in the human body. It has a neural structure that’s very complex and diverse. A neural network spreads through the epidermis, dermis, and subcutaneous tissues. This network generates an exceedingly complex structure.
Feifei Wang +7 more
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SyntheseAbstract Since Clark and Chalmers advanced “The Extended Mind” in 1998, a persistent dispute evolved on how our tool interactions shape the kind of cognition we have. Extended cognition generally views us as cognitively augmented and enhanced by our tool practices, which shall render our cognitive constitution extended to those tools. Bounded
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