Results 91 to 100 of about 3,145,716 (389)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Downstream processing of Isochrysis galbana: a step towards microalgal biorefinery [PDF]

, 2015
An algae-based biorefinery relies on the efficient use of algae biomass through its fractionation of several valuable/bioactive compounds that can be used in industry.
Cifuentes, Alejandro, Fontecha, Javier, Gilbert-López, Bienvenida, Herrero, Miguel, Ibáñez, Elena, Mendiola, José A., Sijtsma, Lolke, Van Den Broek, Lambertus A. M.   +7 more
core   +2 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Complexation of lanthanides, actinides and transition metal cations with a 6-(1,2,4-triazin-3-yl)-2,2’:6’,2’’-terpyridine ligand: implications for actinide(III) /lanthanide(III) partitioning [PDF]

, 2012
The quadridentate N-heterocyclic ligand 6-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-1,2,4-benzotriazin-3-yl)-2,2’:6’,2’’-terpyridine (CyMe4-hemi-BTBP) has been synthesized and its interactions with Am(III), U(VI), Ln(III) and some transition metal cations ...
Albrecht, Albrecht, Alexander, Amoroso, Amoroso, Amoroso, Andreiadis, Banik, Baum, Benay, Benay, Benay, Berthet, Berthet, Berthet, Berthet, Boucher, Calderazzo, Che, Choppin, Choppin, Clint A. Sharrad, Colette, Colette, Colette, Comblin, Constable, Constable, Constable, Constable, Constable, Constable, Constable, Constable, Constable, Constable, Cordier, Cosier, Dam, Daniel Whittaker, Dell'Amico, Dell'Amico, Dell'Amico, Denecke, Denecke, Deneil, Desreux, Desreux, Dolomanov, Drew, Drew, Drew, Drew, Drew, Ekberg, Ekberg, El Aroussi, Ephritikhine, Fife, Foreman, Frank W. Lewis, Françoise Arnaud-Neu, Galaup, Gampp, Gampp, Gampp, Gampp, Gaunt, Geist, Girnt, Giuseppe Modolo, Hagström, Harwood, Heirtzler, Heirtzler, Hubscher-Bruder, Hudson, Hudson, Ionova, Ito, Iveson, Jones, Keizers, Kikuchi, Kolarik, Laurence M. Harwood, Lewis, Lewis, Lewis, Lewis, Madic, Magill, Magnusson, Marcos, Marcos, Mathur, Michael G. B. Drew, Michael J. Hudson, Michal Sypula, Mincher, Mincher, Mukkala, Nash, Nilsson, Pabst, Pabst, Pabst, Palatinus, Peters, Piguet, Pompidor, Potts, Ranganathan, Retegan, Rice, Salvatores, Sheldrick, Stefankiewicz, Steppert, Steppert, Thummel, Trumm, Trumm, Tsang, Vladimira Videva, Véronique Hubscher-Bruder, Walesa-Chorab, Wang   +127 more
core   +2 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Preparation of sisal fiber/polyaniline/bio-surfactant rhamnolipid-layered double hydroxide nanocomposite for water decolorization: kinetic, equilibrium, and thermodynamic studies

Scientific Reports, 2023
Sisal fiber is a potent economical biomaterial for designing composites because of its low density, high specific strength, no toxic effects, and renewability. The present study utilized sisal fiber as a starting material and subjected it to modification
Mehrdad Negarestani, Soheil Tavassoli, Saba Reisi, Negar Beigi, Afsaneh Mollahosseini, Majid Hosseinzadeh, Asiyeh Kheradmand   +6 more
doaj   +1 more source

The effect of ultrasound pretreatment on some selected physicochemical properties of black cumin (Nigella Sativa) [PDF]

, 2018
Background In the present study, the effects of ultrasound pretreatment parameters including irradiation time and power on the quantity of the extracted phenolic compounds quantity as well as on some selected physicochemical properties ...
A Jiménez, AM Goula, AOAC, AOCS, AR Jambrak, AS Oktay, B Khadhraoui, BJ Arends, E Halawani, EA Decker, F Chemat, F Chemat, F Chemat, F Yamaguchi, H Bakhshabadi, H Haron, HRH Takruri, IUPAC, JA Carcel, JL Luque-Garcia, JY Lin, L Han, L Zhang, M Corrales, M Ghavami, M Jacotet-Navarro, M Kebriti, M Pinelo, M Toma, M Vintoru, M Virot, PN Giannelos, S Abdullah, S Machmudah, S Samaram, S Zhao, S Zomorrodi, SK Tiruppur Venkatachallam, SR Shirsath, SU Kadam, TJ Mason, W Lingyun, ZS Zhang   +42 more
core   +1 more source

Extracting Crystal Chemistry from Amorphous Carbon Structures [PDF]

ChemPhysChem, 2017
AbstractCarbon allotropes have been explored intensively by ab initio crystal structure prediction, but such methods are limited by the large computational cost of the underlying density functional theory (DFT). Here we show that a novel class of machine‐learning‐based interatomic potentials can be used for random structure searching and readily ...
Volker L. Deringer, Gábor Csányi, Davide M. Proserpio   +2 more
openaire   +4 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source