Results 121 to 130 of about 909,750 (353)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Chemistry of Protactinium. VIII. Synergistic Effect of Di-isobutyl Carbinol on the Pa(V)-TTA-Benzene Solvent Extraction System [PDF]
Shin Suzuki, Yasushi Inoue
openalex +1 more source
Metabolomics : a tool for studying plant biology [PDF]
In recent years new technologies have allowed gene expression, protein and metabolite profiles in different tissues and developmental stages to be monitored.
Gullberg, Jonas
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
BackgroundLiver cancer remains a major global health burden, with hepatocellular carcinoma (HCC) accounting for approximately 80% of liver cancer cases.
Xuechun Chen +8 more
doaj +1 more source
Aqueous Chemistry of Protactinium(IV). 3. Solvent Extraction of Pa(IV) Perchlorate by Trioctyl Phosphine Oxide. [PDF]
Robert Lundqvist +5 more
openalex +1 more source
Control sustentable poscosecha: extractos de Larrea cuneifolia mediados por nades frente a Botrytis cinerea [PDF]
Botrytis cinerea es un hongo ubicuo que ocasiona la podredumbre gris, una de las principales enfermedades de fruta en poscosecha, siendo responsable de pérdidas económicas. Debido a la creciente preocupación por los efectos adversos del uso de pesticidas,
Boiteux, Joana Jaqueline +4 more
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