Results 131 to 140 of about 2,882,964 (299)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Extraction of high-value compounds from Theobroma grandiflorum (cupuassu) seed shells using pressurized liquid extraction with NADES: a green chemistry approach. [PDF]

Anal Bioanal Chem
Alves Dos Santos PN, Machado Dos Reis MLC, de Moura Pita BL, de Souza Dias F, Fricks AT, Caramão EB.   +5 more
europepmc   +1 more source

Patent-extracted chemistry in PubChem

Updates July 2025 Minor changes but good news in that SureChEMBL 2.0  (bless 'em) now  appears to be updating in PubChem more often and just broke 30 million :) In turn, this brings the total CNER submissions up to 47.7 million and, more importantly, the corroborative intersect between the big three active ...
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Cyclover-Assisted Liquid-Phase Peptide Synthesis Using T3P® as a Green Coupling Reagent. [PDF]

Org Lett
Kushwaha P, Mantel M, Talbiersky P, Li Y, Sharma A, de la Torre BG, Albericio F.   +6 more
europepmc   +1 more source

Extraction chemistry of fermentation product carboxylic acids [PDF]

Biotechnology and Bioengineering, 2009
A S, Kertes, C J, King, Harvey W, Blanch
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Editorial: Advances in natural product chemistry: Yunnan University 100th anniversary

Frontiers in Chemistry, 2023
Wen Chen, Jianwei Dong, Siva S. Panda
doaj   +1 more source

Machine learning prediction and calibration of cellulose-based solid-phase extraction performance for pharmaceuticals across aqueous matrices. [PDF]

RSC Adv
Akor E, Olorunnisola D, Alfred MO, Ejeromedoghene O, Omorogie MO.   +4 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source