Results 71 to 80 of about 3,106,336 (388)
Brewing of filter coffee [PDF]
We report progress on mathematical modelling of coffee grounds in a drip filter coffee machine. The report focuses on the evolution of the shape of the bed of coffee grounds during extraction with some work also carried out on the chemistry of extraction.
Booth, C.+26 more
core
An eco-friendly, tunable and scalable method for producing porous functional nanomaterials designed using molecular interactions [PDF]
Despite significant improvements in the synthesis of templated silica materials, post-synthesis purification remains highly expensive and renders the materials industrially unviable.
Centi, A.+4 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Extraction of Galactolipids from Waste By-Products: The Feasibility of Green Chemistry Methods
Galactolipids are a class of lipids present, inter alia, in the plastid membranes of plant cells. Apart from their biological significance, they are recognized as an important group of bioactive agents, especially in the treatment of osteoarthritis.
Łukasz Woźniak+3 more
doaj +1 more source
Sensitivity of soil phosphorus tests in predicting the potential risk of phosphorus loss from pasture soil [PDF]
The objective of this study was to examine the effects of urine and dung additions on the phosphorus (P) chemistry of pasture land and to compare the sensitivity of two soil extraction methods in assessing the P-loading risk. In a field experiment, urine
Hartikainen, Helinä+3 more
core
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Leveraging Reaction-aware Substructures for Retrosynthesis Analysis [PDF]
Retrosynthesis analysis is a critical task in organic chemistry central to many important industries. Previously, various machine learning approaches have achieved promising results on this task by representing output molecules as strings and autoregressively decoded token-by-token with generative models.
arxiv
Influence of surface stoichiometry and quantum confinement on the electronic structure of small diameter InxGa1-xAs nanowires [PDF]
Electronic structures for InxGa1-xAs nanowires with [100], [110], and [111] orientations and critical dimensions of approximately 2 nm are treated within the framework of density functional theory. Explicit band structures are calculated and properties relevant to nanoelectronic design are extracted including band gaps, effective masses, and density of
arxiv +1 more source
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source