Results 81 to 90 of about 293,237 (309)

Chemical and biological properties of green freshwater alga Ulva intestinalis collected from Casablanca, Morocco

open access: yesEgyptian Journal of Aquatic Research
Ulva intestinalis (U. intestinalis) is a widespread tubular green macroalga that serves as a valuable natural reservoir of carbohydrates, proteins, and minerals, with minimal lipid content.
Mehdi El Mellouki   +4 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

In silico and in vivo anti-inflammatory effect of eugenol and acetyleugenol

open access: yesScientific African
The aim of this study is to assess the anti-inflammatory effects of volatile compounds derived from clove bud in vivo and in silico. Clove bud essential oil was obtained through hydrodistillation and subsequently analyzed using GC–MS.
Achraf Abdou   +9 more
doaj   +1 more source

Investigando cinza da casca do arroz como fase estacionária em cromatografia: uma proposta de aula experimental nos cursos de graduação

open access: yesQuímica Nova, 2012
This article describes an experiment that involves the extraction and separation of the pigments of spinach extract by column chromatography using the silica obtained from rice husk ash as a stationary phase.
João R. de Freitas Filho   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Eco-friendly extraction technologies: A comprehensive review of modern green analytical methods

open access: yesSustainable Chemistry for Climate Action
The current review explores new developments in green analytical chemistry with an emphasis on eco-friendly extraction methods. The study covers solid-phase microextraction (SPME), stir bar sorptive extraction (SBSE), supercritical fluid extraction (SFE),
Binoy Varghese Cheriyan   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Ion Pair Extraction in Preparative Organic Chemistry. V. Alkylation of Dimethyl Benzoylmalonate. [PDF]

open access: bronze, 1969
Arne Brändström   +5 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy