Results 121 to 130 of about 3,783,709 (297)

Effects of Different Extraction Methods on Physicochemical, Functional Properties, and Structure of Dietary Fiber from Dragon Fruit Peel

Shipin gongye ke-ji
To reduce resource waste and enhance the utilization of dragon fruit peel, the study employed acid hydrolysis (A-SDF), enzymatic hydrolysis (E-SDF), and ultrasound-assisted extraction (U-SDF) to isolate soluble dietary fiber (SDF) from red-fleshed dragon
Jiaqi GU, Xiaojun HU, Jiazhuo ZHOU, Yu ZHU, Wei CHEN, Peiyan XIE, Min JIANG, Bei JIN   +7 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A global review of river sediment contamination and remobilization through climate change-induced flooding

Sustainable Environment
A global systematic literature review of river sediment contamination was undertaken, based on secondary data published between 2015 and 2023, to identify the key challenges.
Sadia L. Alfee, Michelle C. Bloor
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Optimization of extraction method for Polygonatum kingianum polysaccharides based on comprehensive functional characteristics

Shipin yu jixie
ObjectiveThis study investigates the effects of various extraction methods on the chemical composition and functional characteristics of polysaccharides derived from Polygonatum kingianum, specifically the white flower and purple-red flower varieties ...
TANG Yayuan, WEI Zhen, YUE Jian, SU Juan, SUN Jian, HE Xuemei   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Extraction, purification, structural characterization, bioactivities, modifications and structure–activity relationship of polysaccharides from Ophiopogon japonicus: a review

Frontiers in Nutrition
Ophiopogon japonicus (Thunb.) Ker Gawl., is a traditional Chinese medicine (TCM) with a history of thousands of years. O. japonicus polysaccharides (OJPs), as one of the main active ingredient, are a kind of representative pharmacological bioactive ...
Yiqiang Zhang, Bo Chen, Bo Chen, Hua Zhang, Juan Zhang, Juan Xue, Juan Xue   +6 more
doaj   +1 more source

DNA Extraction Methods

Proceedings of the West Virginia Academy of Science
KATIE LONG and MARK FLOOD, Forensic Science Program, Fairmont State University, Fairmont, WV 26554. Evaluation of DNA Extraction Methods.  Three forms of DNA extraction types include solution-based, column-based, and magnetic bead-based methodologies, with the latter being the accepted methodology used in forensic laboratories. Magnetic bead-based DNA
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of Extraction Methods on Polyphenol Contents and Antioxidant Activities of Melissa Officinalis and Evaluation of Their Antihypoxic Activities in Mice [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: The role of free radicals in causing many diseases has been well proven. These particles can destroy biomolecules. Antioxidants can prevent these harmful effects.
Ali Mirzazadeh, Mohammad Hossein Hosseinzadeh, Mohammad Eghbali, Mohammad Ali Ebrahimzadeh, Omran Habibi, Ahmad Ramezani, Amin Barani   +6 more
doaj