Results 101 to 110 of about 35,575 (296)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Anatomy, drying behaviour and mechanical properties of lesser used wood species from Mozambique [PDF]
, 2010 The study provides an overview of Mozambique timber sector, descriptive and comparative wood anatomy, drying experiments and interrelationships between mechanics, density and anatomical features of lesser used species from Mozambique.
Uetimane Junior, Ernesto
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Role of Supply Constraints in Multiplier Analysis [PDF]
Multiplier analysis based upon the information contained in Leontief's inverse is undoubtedly part of the core of the input-output methodology and numerous applications an extensions have been developed that exploit its informational content. Nonetheless
Ferran Sancho, M. Alejandro Cardenete
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Core-periphery analysis: a tale of two nations [PDF]
, 1996 Bias, unreliability and omission have been documented in traditional sources of trade data; the lack of service data in trade statistics is the most frequently cited shortcoming. Current trade liberalization is likely to exacerbate these deficiencies.
Jacobson, David, Mack, Richard S.
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The Aging of Recycled Fibers [PDF]
, 1980 The object of this thesis is to study the aging of recycled paper, focusing on strength and optical properties. To observe the changes in these properties, the following experimental procedure was used.
Dubbeld, Martha M.
core +1 more source