Results 171 to 180 of about 12,449 (307)

Optimized extraction of Pinus taeda knotwood sawmill residues as source of antifungal compounds. [PDF]

Bioresour Bioprocess
Coniglio R, Rodao JM, Alonso R, Fioritto F, Ruiz KN, Xavier L, Appelt J, Cabrera MN, Clavijo L.   +8 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Chemical Composition and Structural Traits of Leaf Biomass in Selected Asparagaceae Species. [PDF]

Plants (Basel)
Villada-Lozada N, Andrés-Hernández AR, Maceda A.   +2 more
europepmc   +1 more source

CATARACT EXTRACTION [PDF]

British Journal of Ophthalmology, 1943
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Pine Bark as a Lignocellulosic Resource for Polyurethane Production: An Evaluation. [PDF]

Polymers (Basel)
Arshanitsa A, Pals M, Vjalikova A, Vevere L, Bikovens O, Jashina L.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Colloidal stability of Pinus radiata wood extractives Part 1: Effect of extractives composition and process variables

, 2019
This paper presents the results of a study undertaken to investigate the interaction between the various key factors that have been identified to affect wood extractive colloid stability and pitch deposition of wood extractives released in ...
Richardson, DE (15502574), Karen Stack (14749951), Naila Yaqoob (14753608), Trevor Lewis (14742331), Ngwenya, E (15550406)   +4 more
core  

Valorization of Spruce Bark to Environmentally Sustainable Packaging Materials. [PDF]

ACS Sustain Chem Eng
Khalili H, Muangmeesri S, Ramazanova L, Braud L, Samec JSM, Mathew AP.   +5 more
europepmc   +1 more source