Results 71 to 80 of about 5,978 (262)
Abstract Since Clark and Chalmers advanced “The Extended Mind” in 1998, a persistent dispute evolved on how our tool interactions shape the kind of cognition we have. Extended cognition generally views us as cognitively augmented and enhanced by our tool practices, which shall render our cognitive constitution extended to those tools. Bounded
openaire +2 more sources
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
ANALISIS KOMPONEN KIMIA DARI KAYU SENGON DAN KAYU KARET PADA BEBERAPA MACAM UMUR
This paper reported the result of chemical analysis from sengon (Paraserianthes falcataria) and rubber wood (Hevea brasiliensis) with several age groups.
Gustan Pari
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Characterization of pacific silver fir impregnated with extractives from western redcedar
Alternative and higher value uses are needed for residual materials generated from wood products processing. Western redcedar sawdust contains an array of unique chemicals and has the potential to be used to alter the appearance, stability and ...
Rod Stirling, Stacey Kus
doaj
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Studies on wood durability have highlighted the use of new environmentally friendly substances. In this sense, research carried out with Amazonian forest species is extremely important for the discovery of new bioactive substances from durable wood and ...
Victor Fassina Brocco +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

